FB2026_03 , released September 17, 2026
CV Term Report
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General Information
Term RNA catabolic process ID (Ontology) GO:0006401 (Gene Ontology)
Definition The chemical reactions and pathways resulting in the breakdown of RNA, ribonucleic acid, one of the two main type of nucleic acid, consisting of a long, unbranched macromolecule formed from ribonucleotides joined in 3',5'-phosphodiester linkage.[ ISBN:0198506732 ]
Also Known As"RNA breakdown" ; "RNA catabolism" ; "RNA degradation"
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Data ClassFieldDirect annotations
Genes (FBgn)GO_BIOLOGICAL_PROCESS
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 RNA catabolic process (all annotations which use CV term, excluding "NOT" statements)
     involved_in | RNA catabolic process
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Vocabulary search 
macromolecule catabolic process
 |__nucleic acid catabolic process________________
nucleobase-containing compound catabolic process  |
 |__nucleic acid catabolic process________________|
nucleic acid metabolic process                    |
 |__RNA metabolic process_________________________|
 |__nucleic acid catabolic process________________|
                                                  RNA catabolic process  194 rec.
                                                   |__21U-RNA catabolic process
                                                   |__CUT catabolic process 4 rec.
                                                   |   |__nuclear polyadenylation-dependent CUT catabolic process 2 rec.
                                                   |__DNA replication, removal of RNA primer 1 rec.
                                                   |   |__removal of RNA primer involved in mitotic DNA replication
                                                   |__lncRNA catabolic process 2 rec.
                                                   |   |__nuclear lncRNA surveillance
                                                   |__miRNA catabolic process 9 rec.
                                                   |   |__regulation of miRNA catabolic process(+) 2 rec.
                                                   |   |__target-directed miRNA degradation 6 rec.
                                                   |__mitochondrial RNA catabolic process 8 rec.
                                                   |   |__mitochondrial mRNA catabolic process(+) 4 rec.
                                                   |   |__mitochondrial RNA surveillance(+) 1 rec.
                                                   |   |__regulation of mitochondrial RNA catabolic process(+) 2 rec.
                                                   |__mRNA catabolic process 146 rec.
                                                   |   |__maternal mRNA clearance 4 rec.
                                                   |   |__mitochondrial mRNA catabolic process(+) 4 rec.
                                                   |   |__nuclear-transcribed mRNA catabolic process(+) 75 rec.
                                                   |   |__polyadenylation-dependent mRNA catabolic process(+)
                                                   |   |__polyuridylation-dependent mRNA catabolic process(+) 2 rec.
                                                   |   |__regulation of mRNA catabolic process(+) 93 rec.
                                                   |__polyadenylation-dependent RNA catabolic process 2 rec.
                                                   |   |__cytoplasmic polyadenylation-dependent RNA catabolic process(+)
                                                   |   |__polyadenylation-dependent ncRNA catabolic process(+) 2 rec.
                                                   |__pre-mRNA catabolic process 3 rec.
                                                   |__regulation of RNA stability 95 rec.
                                                   |   |__regulation of mRNA stability(+) 90 rec.
                                                   |   |__regulation of rRNA stability(+)
                                                   |   |__regulation of tRNA stability(+) 2 rec.
                                                   |   |__RNA destabilization(+) 75 rec.
                                                   |   |__RNA stabilization(+) 12 rec.
                                                   |__RNA fragment catabolic process
                                                   |__RNA surveillance 40 rec.
                                                   |   |__cytoplasmic RNA surveillance(+) 1 rec.
                                                   |   |__nuclear RNA surveillance(+) 38 rec.
                                                   |   |__tRNA surveillance(+) 6 rec.
                                                   |__rRNA catabolic process 7 rec.
                                                   |   |__cytoplasmic polyadenylation-dependent rRNA catabolic process
                                                   |   |__nonfunctional rRNA decay
                                                   |   |__regulation of rRNA catabolic process(+)
                                                   |__siRNA catabolic process
                                                   |__sno(s)RNA catabolic process 2 rec.
                                                   |   |__nuclear polyadenylation-dependent snoRNA catabolic process 2 rec.
                                                   |__snRNA catabolic process 2 rec.
                                                   |   |__nuclear polyadenylation-dependent snRNA catabolic process 2 rec.
                                                   |__tRNA decay 9 rec.
                                                       |__regulation of tRNA catabolic process(+) 2 rec.
                                                       |__tRNA surveillance(+) 6 rec.
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Is a RNA metabolic process
nucleic acid catabolic process
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Synonyms
  • "RNA breakdown" EXACT
    "RNA catabolism" EXACT
    "RNA degradation" EXACT
Secondary IDs
hide External Crossreferences & Linkouts
Reactome:R-HSA-9930044 "Nuclear RNA decay"