FB2026_02 , released June 18, 2026
FB2026_02 , released June 18, 2026
CV Term Report
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General Information
Term NADH dehydrogenase (ubiquinone) activity ID (Ontology) GO:0008137 (Gene Ontology)
Definition Catalysis of the reaction: NADH + ubiquinone + 5 H+(in) = NAD+ + ubiquinol + 4 H+(out).
Also Known As "ubiquinone reductase activity"
Comment
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Annotations
Records annotated with this term OR any of its CHILD TERMS
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Data Class Field Records
Genes (FBgn)  GO_MOLECULAR_FUNCTION      20
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 Full annotation statements 
Relevant FlyBase reports
 Gene Groups Genes
 NADH dehydrogenase (ubiquinone) activity (all annotations which use CV term, excluding "NOT" statements)       4     20
     contributes_to | NADH dehydrogenase (ubiquinone) activity       --       7
     enables | NADH dehydrogenase (ubiquinone) activity       --      17
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molecular_function
 |__electron transfer activity___________________________________________________________
monoatomic cation transmembrane transporter activity                                     |
 |__proton transmembrane transporter activity____________________________________________|
monoatomic ion transmembrane transporter activity                                        |
 |__active monoatomic ion transmembrane transporter activity_____________________________|
primary active transmembrane transporter activity                                        |
 |__oxidoreduction-driven active transmembrane transporter activity______________________|
 |__active monoatomic ion transmembrane transporter activity_____________________________|
oxidoreductase activity, acting on NAD(P)H                                               |
 |__NADH dehydrogenase activity__________________________________________________________|
 |__oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor__|
                                                                                         NADH dehydrogenase (ubiquinone) activity  24 rec.
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Is a NADH dehydrogenase activity
electron transfer activity
proton transmembrane transporter activity
oxidoreduction-driven active transmembrane transporter activity
oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor
active monoatomic ion transmembrane transporter activity
Part of
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Synonyms
  • "coenzyme Q reductase activity" RELATED[ EC:7 ]
    "complex 1 dehydrogenase activity" RELATED[ EC:7 ]
    "complex I (electron transport chain) activity" RELATED[ EC:7 ]
    "complex I (mitochondrial electron transport) activity" RELATED[ EC:7 ]
    "complex I (NADH:Q1 oxidoreductase) activity" RELATED[ EC:7 ]
    "dihydronicotinamide adenine dinucleotide-coenzyme Q reductase activity" RELATED[ EC:7 ]
    "DPNH-coenzyme Q reductase activity" RELATED[ EC:7 ]
    "DPNH-ubiquinone reductase activity" RELATED[ EC:7 ]
    "electron transfer complex I activity" RELATED[ EC:7 ]
    "mitochondrial electron transport complex 1 activity" NARROW[ EC:7 ]
    "mitochondrial electron transport complex I activity" NARROW[ EC:7 ]
    "NADH coenzyme Q1 reductase activity" RELATED[ EC:7 ]
    "NADH-coenzyme Q oxidoreductase activity" RELATED[ EC:7 ]
    "NADH-coenzyme Q reductase activity" RELATED[ EC:7 ]
    "NADH-CoQ oxidoreductase activity" RELATED[ EC:7 ]
    "NADH-CoQ reductase activity" RELATED[ EC:7 ]
    "NADH-Q6 oxidoreductase activity" RELATED[ EC:7 ]
    "NADH-ubiquinone oxidoreductase activity" RELATED[ EC:7 ]
    "NADH-ubiquinone reductase activity" RELATED[ EC:7 ]
    "NADH-ubiquinone-1 reductase activity" RELATED[ EC:7 ]
    "NADH:ubiquinone oxidoreductase activity" RELATED[ EC:7 ]
    "NADH:ubiquinone oxidoreductase complex activity" RELATED[ EC:7 ]
    "reduced nicotinamide adenine dinucleotide-coenzyme Q reductase activity" RELATED[ EC:7 ]
    "type 1 dehydrogenase activity" RELATED[ EC:7 ]
    "ubiquinone reductase activity" EXACT
Secondary IDs
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EC:7.1.1.2
MetaCyc:NADH-DEHYDROG-A-RXN
Reactome:R-HSA-163217 "Complex I oxidises NADH to NAD+, reduces CoQ to CoQH2"
RHEA:29091