FB2026_03 , released September 17, 2026

CV Term Report

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General Information

Term

ubiquitin-like modifier activating enzyme activity

ID (Ontology)

GO:0008641 (Gene Ontology)

Definition

Catalysis of the activation of small proteins, such as ubiquitin or ubiquitin-like proteins, through the formation of an ATP-dependent high-energy thiolester bond.

Comment

Links to External Ontologies

QuickGO data AmiGO data

Annotations

Records annotated with this term OR any of its CHILD TERMS

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Results list data from multiple species. Choose a record type above to open its HitList.

Direct annotations: records annotated with this exact term (child terms are NOT included)

Data Class	Field	Direct annotations
Genes (FBgn)	GO_MOLECULAR_FUNCTION

Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records

Full annotation statements	Relevant FlyBase reports
Full annotation statements	Gene Groups	Genes
ubiquitin-like modifier activating enzyme activity (all annotations which use CV term, excluding "NOT" statements)
enables \| ubiquitin-like modifier activating enzyme activity	--

Spanning Tree (Parents/Children)

molecular_function
 |__ATP-dependent activity________________________
catalytic activity                                |
 |__catalytic activity, acting on a protein_______|
ligase activity                                   |
 |__ligase activity, forming carbon-sulfur bonds__|
                                                  ubiquitin-like modifier activating enzyme activity  16 rec.
                                                   |__Atg8 activating enzyme activity 2 rec.
                                                   |__Atg12 activating enzyme activity 2 rec.
                                                   |__FAT10 activating enzyme activity
                                                   |__Hub1 activating enzyme activity
                                                   |__ISG15 activating enzyme activity
                                                   |__NEDD8 activating enzyme activity 3 rec.
                                                   |__SUMO activating enzyme activity 3 rec.
                                                   |__ubiquitin activating enzyme activity 3 rec.
                                                   |__UFM1 activating enzyme activity 2 rec.
                                                   |__URM1 activating enzyme activity 2 rec.

Spanning Tree View Settings
Parents/Children View Depth	Show hierarchy levels: for parents, for children
Relationships
Is a	ligase activity, forming carbon-sulfur bonds catalytic activity, acting on a protein ATP-dependent activity
Part of
Synonyms & Secondary IDs
Synonyms
	"small protein activating enzyme activity" NARROW
Secondary IDs

External Crossreferences & Linkouts