FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
CV Term Report
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General Information
Term hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds ID (Ontology) GO:0016810 (Gene Ontology)
Definition Catalysis of the hydrolysis of any carbon-nitrogen bond, C-N, with the exception of peptide bonds.[ EC:3 ]
Comment
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Annotations
Records annotated with this term OR any of its CHILD TERMS
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Data Class Field Records
Genes (FBgn)  GO_MOLECULAR_FUNCTION       8
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 Full annotation statements 
Relevant FlyBase reports
 Gene Groups Genes
 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds (all annotations which use CV term, excluding "NOT" statements)       1      8
     enables | hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds       --       8
Spanning Tree (Parents/Children)
Only view relationship: 
  catalytic activity
   |__hydrolase activity
       |__hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds  107 rec.
           |__(S)-norcoclaurine synthase activity
           |__deacetylipecoside synthase activity
           |__deacetylisoipecoside synthase activity
           |__deaminase activity 21 rec.
           |   |__1-aminocyclopropane-1-carboxylate deaminase activity
           |   |__1-pyrroline-4-hydroxy-2-carboxylate deaminase activity
           |   |__2'-deoxyadenosine deaminase activity
           |   |__2-aminomuconate deaminase activity
           |   |__2-iminobutanoate/2-iminopropanoate deaminase activity(+) 1 rec.
           |   |__5'-deoxyadenosine deaminase activity
           |   |__5'-methylthioadenosine deaminase activity
           |   |__adenine deaminase activity
           |   |__adenosine deaminase activity(+) 10 rec.
           |   |__adenosine-phosphate deaminase activity(+) 1 rec.
           |   |__blasticidin-S deaminase activity
           |   |__cAMP deaminase activity
           |   |__creatinine deaminase activity
           |   |__cytidine deaminase activity 4 rec.
           |   |__cytosine deaminase activity
           |   |__dCMP deaminase activity 1 rec.
           |   |__dCTP deaminase (dUMP-forming) activity
           |   |__dCTP deaminase activity
           |   |__diaminohydroxyphosphoribosylaminopyrimidine deaminase activity
           |   |__dihydropterin deaminase activity 1 rec.
           |   |__double-stranded RNA adenosine deaminase activity 2 rec.
           |   |__glucosamine-6-phosphate deaminase activity 1 rec.
           |   |__guanine deaminase activity 1 rec.
           |   |__guanosine deaminase activity
           |   |__isoguanine deaminase activity
           |   |__methylenediurea deaminase activity
           |   |__N6-methyl-AMP deaminase activity
           |   |__pterin deaminase activity
           |   |__pyrithiamine deaminase activity
           |   |__S-adenosylhomocysteine deaminase activity
           |   |__sepiapterin deaminase activity
           |__hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides 6 rec.
           |   |__2,5-dioxopiperazine hydrolase activity
           |   |__5-oxoprolinase (ATP-hydrolyzing) activity 1 rec.
           |   |__6-aminohexanoate-cyclic-dimer hydrolase activity
           |   |__allantoinase activity 1 rec.
           |   |__barbiturase activity
           |   |__beta-lactamase activity
           |   |__carboxymethylhydantoinase activity
           |   |__creatininase activity
           |   |__cyanuric acid amidohydrolase activity
           |   |__dihydroorotase activity 1 rec.
           |   |__dihydropyrimidinase activity 1 rec.
           |   |__enamidase activity
           |   |__epsilon-caprolactam lactamase activity
           |   |__hydroxyisourate hydrolase activity 1 rec.
           |   |__imidazolone hydrolase activity
           |   |__imidazolonepropionase activity
           |   |__L-lysine-lactamase activity
           |   |__maleimide hydrolase activity
           |   |__N-methylhydantoinase (ATP-hydrolyzing) activity
           |   |__xanthine hydrolase activity
           |__hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines 23 rec.
           |   |__1-pyrroline-4-hydroxy-2-carboxylate deaminase activity
           |   |__2'-deoxyadenosine deaminase activity
           |   |__5'-deoxyadenosine deaminase activity
           |   |__5'-methylthioadenosine deaminase activity
           |   |__8-oxoguanine deaminase activity
           |   |__adenine deaminase activity
           |   |__adenosine deaminase activity(+) 10 rec.
           |   |__adenosine-phosphate deaminase activity(+) 1 rec.
           |   |__aminoimidazolase activity
           |   |__blasticidin-S deaminase activity
           |   |__cAMP deaminase activity
           |   |__creatinine deaminase activity
           |   |__cyclohydrolase activity(+) 4 rec.
           |   |__cytidine deaminase activity 4 rec.
           |   |__cytosine deaminase activity
           |   |__dCMP deaminase activity 1 rec.
           |   |__dCTP deaminase (dUMP-forming) activity
           |   |__dCTP deaminase activity
           |   |__diaminohydroxyphosphoribosylaminopyrimidine deaminase activity
           |   |__dihydropterin deaminase activity 1 rec.
           |   |__guanine deaminase activity 1 rec.
           |   |__guanosine deaminase activity
           |   |__isoguanine deaminase activity
           |   |__N-cyclopropylammelide alkylamino hydrolase activity
           |   |__N-cyclopropylammeline deaminase activity
           |   |__N-cyclopropylmelamine deaminase activity
           |   |__pterin deaminase activity
           |   |__pyrithiamine deaminase activity
           |   |__S-adenosylhomocysteine deaminase activity
           |   |__sepiapterin deaminase activity
           |__hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides 70 rec.
           |   |__(S)-N-acetyl-1-phenylethylamine hydrolase activity
           |   |__2-(acetamidomethylene)succinate hydrolase activity
           |   |__2-(hydroxymethyl)-3-(acetamidomethylene)succinate hydrolase activity
           |   |__2-amino-5-formylamino-6-(5-phosphoribosylamino)pyrimidin-4(3H)-one formate-lyase activity
           |   |__4-acetamidobutyrate deacetylase activity
           |   |__4-acetamidobutyryl-CoA deacetylase activity
           |   |__4-methyleneglutaminase activity
           |   |__5-aminopentanamidase activity
           |   |__6-aminohexanoate-dimer hydrolase activity
           |   |__acetylornithine deacetylase activity
           |   |__acetylputrescine deacetylase activity
           |   |__acetylspermidine deacetylase activity
           |   |__aculeacin-A deacylase activity
           |   |__acyl-lysine deacylase activity
           |   |__acylagmatine amidase activity
           |   |__adenosine 5'-monophosphoramidase activity 4 rec.
           |   |__adenosylcobinamide hydrolase activity
           |   |__alkylamidase activity
           |   |__allophanate hydrolase activity
           |   |__amidase activity(+) 5 rec.
           |   |__amino acid conjugated cholate hydrolase activity(+)
           |   |__aminoacylase activity 7 rec.
           |   |__aryl-acylamidase activity
           |   |__arylalkyl acylamidase activity
           |   |__arylformamidase activity 1 rec.
           |   |__aspartoacylase activity
           |   |__beta-alanyl-dopamine hydrolase activity 1 rec.
           |   |__beta-alanyl-histamine hydrolase activity 1 rec.
           |   |__beta-ureidopropionase activity 1 rec.
           |   |__biotinidase activity 1 rec.
           |   |__biuret amidohydrolase activity
           |   |__carnitinamidase activity
           |   |__chenodeoxycholoyltaurine hydrolase activity
           |   |__chitin deacetylase activity 5 rec.
           |   |__chitin disaccharide deacetylase activity
           |   |__choloylglycine hydrolase activity
           |   |__citrullinase activity
           |   |__D-benzoylarginine-4-nitroanilide amidase activity
           |   |__D-glutaminase activity
           |   |__deaminated glutathione amidase activity 1 rec.
           |   |__diacetylchitobiose deacetylase activity
           |   |__fatty acid amide hydrolase activity 6 rec.
           |   |__formylaspartate deformylase activity
           |   |__formylmethionine deformylase activity
           |   |__formyltetrahydrofolate deformylase activity
           |   |__gamma-glutamyl-gamma-aminobutyrate hydrolase activity
           |   |__glutamin-(asparagin-)ase activity
           |   |__glutaminase activity 2 rec.
           |   |__glutaryl-7-aminocephalosporanic-acid acylase activity
           |   |__glutathionylspermidine amidase activity
           |   |__glycosphingolipid deacylase activity
           |   |__hippurate hydrolase activity
           |   |__histone deacetylase activity, hydrolytic mechanism(+) 6 rec.
           |   |__lipoamidase activity
           |   |__long-chain fatty-acyl-glutamate deacylase activity
           |   |__mandelamide amidase activity
           |   |__N(alpha)-benzyloxycarbonylleucine hydrolase activity
           |   |__N,N-dimethylformamidase activity
           |   |__N-(long-chain-acyl)ethanolamine deacylase activity
           |   |__N-acetyl-beta-alanine deacetylase activity
           |   |__N-acetylcitrulline deacetylase activity
           |   |__N-acetyldiaminopimelate deacetylase activity
           |   |__N-acetylgalactosamine-6-phosphate deacetylase activity
           |   |__N-acetylglucosamine deacetylase activity
           |   |__N-acetylglucosamine-6-phosphate deacetylase activity 1 rec.
           |   |__N-acetylglucosaminylinositol deacetylase activity
           |   |__N-acetylglucosaminylphosphatidylinositol deacetylase activity 1 rec.
           |   |__N-acetylmuramoyl-L-alanine amidase activity 8 rec.
           |   |__N-acyl-D-amino-acid deacylase activity
           |   |__N-acyl-D-aspartate deacylase activity
           |   |__N-acyl-D-glutamate deacylase activity
           |   |__N-acylsphingosine amidohydrolase activity 1 rec.
           |   |__N-benzyloxycarbonylglycine hydrolase activity
           |   |__N-carbamoyl-D-amino acid hydrolase activity
           |   |__N-carbamoyl-L-amino-acid hydrolase activity
           |   |__N-carbamoylputrescine amidase activity
           |   |__N-carbamoylsarcosine amidase activity
           |   |__N-feruloylglycine deacylase activity
           |   |__N-formylglutamate deformylase activity
           |   |__N-glutamylanilide hydrolase activity
           |   |__N-malonylurea hydrolase activity
           |   |__N-methyl-2-oxoglutaramate hydrolase activity
           |   |__N-substituted formamide deformylase activity
           |   |__N4-(beta-N-acetylglucosaminyl)-L-asparaginase activity 4 rec.
           |   |__N4-acetylcytidine amidohydrolase activity
           |   |__nicotinamide-nucleotide amidase activity
           |   |__omega-amidase activity(+) 1 rec.
           |   |__pantetheine hydrolase activity 4 rec.
           |   |__pantothenase activity
           |   |__para-aminobenzoyl-glutamate hydrolase activity
           |   |__penicillin amidase activity
           |   |__pentanamidase activity
           |   |__peptide deformylase activity 3 rec.
           |   |__peptide-N4-(N-acetyl-beta-glucosaminyl)asparagine amidase activity 1 rec.
           |   |__peptidyl-glutaminase activity
           |   |__phthalyl amidase activity
           |   |__protein asparagine deamidase activity(+) 2 rec.
           |   |__protein de-2-hydroxyisobutyrylase activity
           |   |__protein decrotonylase activity(+)
           |   |__protein deglycase activity 2 rec.
           |   |__protein-glutamine glutaminase activity
           |   |__protein-malonyllysine demalonylase activity
           |   |__protein-N-terminal glutamine amidohydrolase activity 1 rec.
           |   |__succinyl-diaminopimelate desuccinylase activity
           |   |__succinylglutamate desuccinylase activity
           |   |__theanine hydrolase activity
           |   |__tryptophanamidase activity
           |   |__tubulin deacetylase activity
           |   |__UDP-3-O-acyl-N-acetylglucosamine deacetylase activity
           |   |__urease activity
           |   |__ureidoglycolate hydrolase activity
           |   |__ureidosuccinase activity
           |   |__urethanase activity
           |__hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines 3 rec.
           |   |__2-chloro-4-hydroxy-6-amino-1,3,5-triazine aminohydrolase activity
           |   |__5-ureido-4-imidazole carboxylate hydrolase activity
           |   |__agmatinase activity
           |   |__agmatine deiminase activity
           |   |__allantoate deiminase activity
           |   |__allantoicase activity
           |   |__amidinoaspartase activity
           |   |__aminopropylagmatine ureohydrolase activity
           |   |__ammelide aminohydrolase activity
           |   |__ammeline aminohydrolase activity
           |   |__arginase activity 1 rec.
           |   |__arginine deiminase activity
           |   |__creatinase activity
           |   |__D-arginase activity
           |   |__deisopropylhydroxyatrazine aminohydrolase activity
           |   |__diguanidinobutanase activity
           |   |__dimethylargininase activity 1 rec.
           |   |__formimidoylaspartate deiminase activity
           |   |__formimidoylglutamase activity
           |   |__formimidoylglutamate deiminase activity
           |   |__guanidinoacetase activity
           |   |__guanidinobutyrase activity
           |   |__guanidinopropionase activity
           |   |__methylenediurea deaminase activity
           |   |__methylguanidinase activity
           |   |__N-succinylarginine dihydrolase activity
           |   |__proclavaminate amidinohydrolase activity
           |   |__protein-arginine deiminase activity(+)
           |   |__ureidoglycine aminohydrolase activity
           |__hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in nitriles
           |   |__nitrilase activity(+)
           |   |__thiocyanate hydrolase activity
           |__hydroxydechloroatrazine ethylaminohydrolase activity
           |__IAA-amino acid conjugate hydrolase activity
           |   |__IAA-Ala conjugate hydrolase activity
           |   |__IAA-Leu conjugate hydrolase activity
           |   |__IAA-Phe conjugate hydrolase activity
           |__jasmonic acid hydrolase activity
           |__jasmonyl-Ile conjugate hydrolase activity
           |__N-acetyl-anhydromuramoyl-L-alanine amidase activity
           |__N-isopropylammelide isopropylaminohydrolase activity
           |__riboflavinase activity
           |__strictosidine synthase activity
           |__thiaminase activity
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Synonyms
  • "hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in other compounds" NARROW
Secondary IDs
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EC:3.5.-.-
Reactome:R-HSA-6803753 "NAAA hydrolyses NAEs to FAs and ethanolamine"