FB2026_03 , released September 17, 2026

CV Term Report

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General Information

Term

melanization defense response

ID (Ontology)

GO:0035006 (Gene Ontology)

Definition

The blackening of the wounded area of the cuticle or the surface of invading pathogens, parasites or parasitoids, resulting from a proteolytic cascade leading to the de novo synthesis and deposition of melanin.[ PubMed:12408809 ]

Also Known As

"melanization defence response"

Comment

Links to External Ontologies

QuickGO data AmiGO data

Annotations

Records annotated with this term OR any of its CHILD TERMS

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Results list data from multiple species. Choose a record type above to open its HitList.

Direct annotations: records annotated with this exact term (child terms are NOT included)

Data Class	Field	Direct annotations
Genes (FBgn)	GO_BIOLOGICAL_PROCESS

Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records

Full annotation statements	Relevant FlyBase reports
Full annotation statements	Gene Groups	Genes
melanization defense response (all annotations which use CV term, excluding "NOT" statements)
involved_in \| melanization defense response	--
NOT \| involved_in \| melanization defense response	--

Spanning Tree (Parents/Children)

immune response
 |__innate immune response____________________
phenol-containing compound metabolic process  |
 |__melanin metabolic process_________________|
secondary metabolic process                   |
 |__melanin metabolic process_________________|
pigment metabolic process                     |
 |__melanin metabolic process_________________|
defense response to symbiont                  |
 |__innate immune response____________________|
                                              melanization defense response  58 rec.
                                               |__melanotic encapsulation of foreign target 32 rec.
                                               |   |__regulation of melanotic encapsulation of foreign target(+) 3 rec.
                                               |__regulation of melanization defense response 13 rec.
                                                   |__negative regulation of melanization defense response(+) 5 rec.
                                                   |__positive regulation of melanization defense response 7 rec.
                                                   |__regulation of melanotic encapsulation of foreign target(+) 3 rec.

Spanning Tree View Settings
Parents/Children View Depth	Show hierarchy levels: for parents, for children
Relationships
Is a	melanin metabolic process innate immune response
Part of
Synonyms & Secondary IDs
Synonyms
	"melanization defence response" EXACT
Secondary IDs

External Crossreferences & Linkouts