FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
CV Term Report
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General Information
Term proteasome-activating activity ID (Ontology) GO:0036402 (Gene Ontology)
Definition Catalysis of the reaction: ATP + H2O = ADP + phosphate, which promotes unfolding of protein substrates, and channel opening of the core proteasome.[ PubMed:11430818 ]
Also Known As "ATPase involved in positive regulation of proteasomal protein catabolic process" ; "proteasomal ATPase activity" ; "proteasome-activating ATPase activity"
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Annotations
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Data Class Field Records
Genes (FBgn)  GO_MOLECULAR_FUNCTION       9
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 Full annotation statements 
Relevant FlyBase reports
 Gene Groups Genes
 proteasome-activating activity (all annotations which use CV term, excluding "NOT" statements)       1      9
     enables | proteasome-activating activity       --       9
Spanning Tree (Parents/Children)
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molecular_function
 |__ATP-dependent activity___________________________________
macromolecular conformation isomerase activity               |
 |__polypeptide conformation or assembly isomerase activity__|
                                                             proteasome-activating activity  10 rec.
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Is a polypeptide conformation or assembly isomerase activity
ATP-dependent activity
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Synonyms
  • "ATPase involved in positive regulation of proteasomal protein catabolic process" EXACT
    "proteasomal ATPase activity" EXACT
    "proteasome channel gating activity" NARROW
    "proteasome channel opening activity" NARROW
    "proteasome-activating ATPase activity" EXACT
Secondary IDs
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EC:5.6.1.5