FB2026_02 , released June 18, 2026

CV Term Report

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General Information

Term

apical junction complex

ID (Ontology)

GO:0043296 (Gene Ontology)

Definition

A functional unit located near the cell apex at the points of contact between epithelial cells, which in vertebrates is composed of the tight junction, the zonula adherens, and desmosomes and in some invertebrates, such as Drosophila, is composed of the subapical complex (SAC), the zonula adherens and the septate junction. Functions in the regulation of cell polarity, tissue integrity and intercellular adhesion and permeability.[ PubMed:12525486 PubMed:15196556 ]

Also Known As

"apical cell junction complex" ; "apical junction"

Comment

Links to External Ontologies

QuickGO data AmiGO data

Annotations

Records annotated with this term OR any of its CHILD TERMS

Choose a record type to view annotations for this term and its child terms. Direct annotations and full annotation statements below also provide HitList buttons.

Results list data from multiple species. Choose a record type above to open its HitList.

Direct annotations: records annotated with this exact term (child terms are NOT included)

Data Class	Field	Direct annotations
Genes (FBgn)	GO_CELLULAR_COMPONENT

Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records

Full annotation statements	Relevant FlyBase reports
Full annotation statements	Genes
apical junction complex (all annotations which use CV term, excluding "NOT" statements)
colocalizes_with \| apical junction complex
is_active_in \| apical junction complex
located_in \| apical junction complex

Spanning Tree (Parents/Children)

  anchoring junction
   |__cell-cell junction
       |__apical junction complex  139 rec.
           |__bicellular tight junction 2 rec.
           |   |__host-symbiont bicellular tight junction
           |__septate junction 97 rec.
           |   |__pleated septate junction 13 rec.
           |   |__smooth septate junction 17 rec.
           |__subapical complex 11 rec.
           |__zonula adherens 33 rec.
               |__puncta adhaerentia

Spanning Tree View Settings
Parents/Children View Depth	Show hierarchy levels: for parents, for children
Relationships
Is a	cell-cell junction
Part of
Synonyms & Secondary IDs
Synonyms
	"apical cell junction complex" EXACT "apical junction" EXACT
Secondary IDs

External Crossreferences & Linkouts