FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
CV Term Report
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General Information
Term glutathione dehydrogenase (ascorbate) activity ID (Ontology) GO:0045174 (Gene Ontology)
Definition Catalysis of the reaction: dehydroascorbate + 2 glutathione = L-ascorbate + glutathione disulfide.
Also Known As "dehydroascorbate reductase activity"
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Annotations
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Data Class Field Records
Genes (FBgn)  GO_MOLECULAR_FUNCTION       4
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 Gene Groups Genes
 glutathione dehydrogenase (ascorbate) activity (all annotations which use CV term, excluding "NOT" statements)       1      4
     enables | glutathione dehydrogenase (ascorbate) activity       --       4
Spanning Tree (Parents/Children)
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molecular_function
 |__antioxidant activity__________________________________________________________________________________
disulfide oxidoreductase activity                                                                         |
 |__glutathione disulfide oxidoreductase activity_________________________________________________________|
oxidoreductase activity, acting on a sulfur group of donors                                               |
 |__oxidoreductase activity, acting on a sulfur group of donors, quinone or similar compound as acceptor__|
                                                                                         glutathione dehydrogenase (ascorbate) activity  5 rec.
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Is a glutathione disulfide oxidoreductase activity
antioxidant activity
oxidoreductase activity, acting on a sulfur group of donors, quinone or similar compound as acceptor
Part of
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Synonyms
  • "dehydroascorbate reductase activity" EXACT
    "dehydroascorbic acid reductase activity" RELATED[ EC:1 ]
    "dehydroascorbic reductase activity" RELATED[ EC:1 ]
    "DHA reductase activity" RELATED[ EC:1 ]
    "GDOR" RELATED[ EC:1 ]
    "glutathione dehydroascorbate reductase activity" RELATED[ EC:1 ]
    "glutathione:dehydroascorbate oxidoreductase activity" RELATED[ EC:1 ]
    "glutathione:dehydroascorbic acid oxidoreductase activity" RELATED[ EC:1 ]
Secondary IDs
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EC:1.8.5.1
KEGG_REACTION:R01108
MetaCyc:1.8.5.1-RXN
Reactome:R-HSA-198813 "GSTO dimers reduce DeHA to AscH-"
RHEA:24424