FB2026_03 , released September 17, 2026
CV Term Report
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General Information
Term peptidoglycan recognition protein signaling pathway ID (Ontology) GO:0061057 (Gene Ontology)
Definition The series of molecular signals initiated by binding of peptidoglycan to a receptor and ending with regulation of a downstream cellular process. The main outcome of the Imd signaling is the production of antimicrobial peptides.[ PubMed:18688280 PubMed:24706930 ]
Also Known As"Imd signaling pathway" ; "Imd signalling pathway"
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Genes (FBgn)GO_BIOLOGICAL_PROCESS
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 peptidoglycan recognition protein signaling pathway (all annotations which use CV term, excluding "NOT" statements)
     involved_in | peptidoglycan recognition protein signaling pathway       --
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innate immune response-activating signaling pathway
 |__pattern recognition receptor signaling pathway__
defense response                                    |
 |__defense response to bacterium___________________|
response to bacterium                               |
 |__defense response to bacterium___________________|
                                                    peptidoglycan recognition protein signaling pathway  85 rec.
                                                     |__regulation of peptidoglycan recognition protein signaling pathway 65 rec.
                                                         |__negative regulation of peptidoglycan recognition protein signaling pathway 45 rec.
                                                         |__positive regulation of peptidoglycan recognition protein signaling pathway 21 rec.
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Is a pattern recognition receptor signaling pathway
Part of defense response to bacterium
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Synonyms
  • "Imd signaling pathway" EXACT
    "Imd signalling pathway" EXACT
    "immune deficiency pathway" RELATED
    "immune deficiency signaling pathway" RELATED
    "PGRP signaling pathway" RELATED
Secondary IDs
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