FB2026_03 , released September 17, 2026

CV Term Report

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General Information

Term

2-hydroxyacyl-CoA lyase activity

ID (Ontology)

GO:0106359 (Gene Ontology)

Definition

Catalysis of the reaction: a 2-hydroxy fatty acyl-CoA = a fatty aldehyde + formyl-CoA. The reaction acts on 2-hydroxy-3-methyl-branched fatty acyl-CoA and 2-hydroxy-long-chain fatty acyl-CoA.[ EC:4 PubMed:21708296 PubMed:28289220 ]

Comment

Links to External Ontologies

QuickGO data AmiGO data

Annotations

Records annotated with this term OR any of its CHILD TERMS

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Results list data from multiple species. Choose a record type above to open its HitList.

Direct annotations: records annotated with this exact term (child terms are NOT included)

Data Class	Field	Direct annotations
Genes (FBgn)	GO_MOLECULAR_FUNCTION

Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records

Full annotation statements	Relevant FlyBase reports
Full annotation statements	Genes
2-hydroxyacyl-CoA lyase activity (all annotations which use CV term, excluding "NOT" statements)
enables \| 2-hydroxyacyl-CoA lyase activity

Spanning Tree (Parents/Children)

  carbon-carbon lyase activity
   |__aldehyde-lyase activity
       |__2-hydroxyacyl-CoA lyase activity  1 rec.
           |__2-hydroxyphytanoyl-CoA lyase activity

Spanning Tree View Settings
Parents/Children View Depth	Show hierarchy levels: for parents, for children
Relationships
Is a	aldehyde-lyase activity
Part of
Synonyms & Secondary IDs
Synonyms

Secondary IDs

External Crossreferences & Linkouts
	EC:4.1.2.63 RHEA:25375 RHEA:25379 RHEA:67444 RHEA:67448