FB2026_03 , released September 17, 2026
CV Term Report
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General Information
Term molecular sensor activity ID (Ontology) GO:0140299 (Gene Ontology)
Definition Binding to a molecule and eliciting a change in the protein's activity in response to the intracellular level of that molecule.[ PubMed:26328879 ]
Also Known As"small molecular sensor activity" ; "small molecule sensing activity"
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Data ClassFieldDirect annotations
Genes (FBgn)GO_MOLECULAR_FUNCTION
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 Genes
 molecular sensor activity (all annotations which use CV term, excluding "NOT" statements)
     enables | molecular sensor activity
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  molecular_function
   |__molecular function regulator activity
       |__molecular sensor activity  34 rec.
           |__amino acid sensor activity 2 rec.
           |   |__glutamine sensor activity
           |   |__tryptophan sensor activity
           |   |__tyrosine sensor activity
           |   |__valine sensor activity
           |__carbon monoxide sensor activity
           |__DNA damage sensor activity 14 rec.
           |   |__ATP-dependent DNA damage sensor activity 13 rec.
           |__glucose sensor activity
           |__inositol pyrophosphate sensor activity
           |__lipid sensor activity
           |   |__phosphatidylinositol-4,5-bisphosphate sensor activity
           |   |__sterol sensor activity
           |__membrane curvature sensor activity 2 rec.
           |__metal ion sensor activity 12 rec.
           |   |__cadmium ion sensor activity
           |   |__calcium ion sensor activity 11 rec.
           |   |__copper ion sensor activity
           |   |__iron sensor activity
           |   |__zinc ion sensor activity 1 rec.
           |__nitric oxide sensor activity
           |__osmosensor activity 1 rec.
           |   |__osmolarity-sensing monoatomic cation channel activity
           |__oxygen sensor activity 1 rec.
           |__peroxide sensor activity
           |__phosphorelay sensor kinase activity
           |__stalled ribosome sensor activity 1 rec.
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Is a molecular function regulator activity
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Synonyms
  • "small molecular sensor activity" EXACT
    "small molecule sensing activity" EXACT
    "small molecule sensor activity" NARROW
Secondary IDs
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Reactome:R-HSA-9854368 "ROS,RNS oxidize ACO2:4Fe-4S"