FB2026_03 , released September 17, 2026

CV Term Report

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General Information

Term

Sec body

ID (Ontology)

GO:7770092 (Gene Ontology)

Definition

A condensate that forms reversibly in the cytoplasm under stress, notably amino acid starvation or salt stress, by coalescence of endoplasmic reticulum exit site (ERES) components including the scaffold protein Sec16 and COPII coat subunits. Sec bodies form through liquid-liquid phase separation and act as a protective reservoir for ERES components, permitting reversible shutdown of the early secretory pathway and promoting cell survival during stress.[ PubMed:25386913 PubMed:31152627 PubMed:36325988 ]

Also Known As

"sec-body"

Comment

Links to External Ontologies

QuickGO data AmiGO data

Annotations

Records annotated with this term OR any of its CHILD TERMS

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Direct annotations: records annotated with this exact term (child terms are NOT included)

Data Class	Field	Direct annotations
Genes (FBgn)	GO_CELLULAR_COMPONENT

Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records

Full annotation statements	Relevant FlyBase reports
Full annotation statements	Genes
Sec body (all annotations which use CV term, excluding "NOT" statements)
located_in \| Sec body

Spanning Tree (Parents/Children)

intracellular anatomical structure
 |__cytoplasm_____________________________
membraneless organelle                    |
 |__intracellular membraneless organelle__|
intracellular organelle                   |
 |__intracellular membraneless organelle__|
cellular anatomical structure             |
 |__cytoplasm_____________________________|
                                          Sec body  1 rec.

Spanning Tree View Settings
Parents/Children View Depth	Show hierarchy levels: for parents, for children
Relationships
Is a	intracellular membraneless organelle
Part of	cytoplasm
Synonyms & Secondary IDs
Synonyms
	"sec-body" EXACT
Secondary IDs

External Crossreferences & Linkouts