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General Information
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| Term |
affinity chromatography technology |
ID (Ontology) |
MI:0004 (Molecular Interactions) |
| Definition |
This class of approaches is characterised by the use of affinity resins as tools to purify molecule of interest (baits) and their binding partners. The baits can be captured by a variety of high affinity ligands linked to a resin - for example, antibodies specific for the bait itself, antibodies for specific tags engineered to be expressed as part of the bait or other high affinity binders such as glutathione resins for GST fusion proteins, metal resins for histidine-tagged proteins.[ PubMed:7708014 ] |
| Also Known As |
"affinity chrom" ; "Affinity purification" |
| Comment |
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Links to External Ontologies
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Annotations
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Records annotated with this term OR any of its CHILD TERMS
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Records annotated with this exact term (annotations to child terms are NOT included)
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No relevant records available
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Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records
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| Full annotation statements | Relevant FlyBase reports |
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| Interaction Groups |
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affinity chromatography technology (all annotations which use CV term, excluding "NOT" statements) | 106 |
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Relationships