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General Information
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| Term |
beta galactosidase complementation |
ID (Ontology) |
MI:0010 (Molecular Interactions) |
| Definition |
Beta-galactosidase activity can be used to monitor the interaction of chimeric proteins. Pairs of inactive beta gal deletion mutants are capable of complementing to restore activity when fused to interacting protein partners. Critical to the success of this system is the choice of two poorly complementing mutant moieties, since strongly complementing mutants spontaneously assemble and produce functional beta-gal activity detectable in absence of any fused protein fragment.[ PubMed:12042868 PubMed:9237989 ] |
| Also Known As |
"beta galactosidase" |
| Comment |
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Links to External Ontologies
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Annotations
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Records annotated with this term OR any of its CHILD TERMS
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Records annotated with this exact term (annotations to child terms are NOT included)
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No relevant records available
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Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records
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| Full annotation statements | Relevant FlyBase reports |
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| Interaction Groups |
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beta galactosidase complementation (all annotations which use CV term, excluding "NOT" statements) | 1 |
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Relationships