|Name||of Wallace||FlyBase ID||FBal0001653|
|Feature type||allele||Associated gene||Dmel\ci|
|Allele class||gain of function allele|
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|Nature of the Allele|
|Mutations Mapped to the Genome|
|Associated Sequence Data|
|Nature of the lesion|
Uncharacterised alterations located 5' to the transcription unit and 10kb 3' to the transcription unit.
Single 6.4kb insertion in the PstI HaeIII fragment.
|Caused by insertion|
|Phenotype Manifest In|
Heterozygotes show variable loss of vein L4 tissue.
Heterozygotes show wing vein L4 defects.
When analysed in large clones in the developing eye the packing in the ommatidial clusters is disrupted.
Wings from homozygotes have, at low penetrance, a mirror symmetrical outgrowth composed of anterior wing material, resembling duplications caused by ectopic dpp expression.
Homozygotes occasionally show overgrowth in the anterior compartment of the wing. ciD/ciW flies have abnormal legs.
Lack all longitudinal and transverse veins and affect morphogenesis of legs and eyes.
Homozygote is extreme ci type. Wings sometimes almost twice normal width, arclike, and virtually lack veins. Often present is a well-organized pattern of venation in which the posterior crossvein flows smoothly into L5. Legs lumpy, sex combs larger than normal, antennae enlarged, eyes smaller and extra bristles present. Heterozygote shows gap in L4 in 80% of flies. ciW enhanced by H, en, and Cy (House, 1953c; House 1959) and by Tp(4;Y) (Benner, 1972). Temperature effect described by House (1955b). RK2.
|Phenotype Manifest In|
|NOT suppressed by|
The wing vein L4 defects observed in ciW/+ heterozygotes are enhanced by one copy of cg07659 or cg3.
|Complementation & Rescue Data|
|Fails to complement|
|Stocks ( 2 )|
|Notes on Origin|
Wallace, 20th April 1936.
Weak gain of function allele.
|External Crossreferences & Linkouts|
|Synonyms & Secondary IDs ( 5 )|
|Secondary FlyBase IDs|
|References ( 18 )|