FB2025_01 , released February 20, 2025
Allele: Dmel\wrapperUAS.cNa
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General Information
Symbol
Dmel\wrapperUAS.cNa
Species
D. melanogaster
Name
Saccharomyces cerevisiae UAS construct a of Noordermeer
FlyBase ID
FBal0094261
Feature type
allele
Associated gene
Dmel\wrapper
Associated Insertion(s)
Carried in Construct
P{UAS-wrapper.N}
Also Known As
UAS-wrapper
Key Links
Transgenic product class
cDNA
(Noordermeer et al., 1998)
wild_type
(Noordermeer et al., 1998)
Mutagen
Nature of the Allele
Transgenic product class
cDNA
(Noordermeer et al., 1998)
wild_type
(Noordermeer et al., 1998)
Mutagen
in vitro construct
(Noordermeer et al., 1998)
Progenitor genotype
Carried in construct
P{UAS-wrapper.N}
Cytology
Description

UASt regulatory sequences drive expression of a 1.9kb XhoI-XbaI full length wrapper cDNA.

(Noordermeer et al., 1998)
Allele components
Component
Use(s)
Regulatory region(s)
UASt
Encoded product / tool
wrapper
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Embryos expressing wrapperScer\UAS.cNa under the control of Scer\GAL4elav.PLu show death of some midline glia and fusion of some commissures. Some neurons and possibly glia in the lateral region of the central nervous system also die in these embryos. A similar phenotype is seen in embryos expressing wrapperScer\UAS.cNa under the control of Scer\GAL4sca-537.4. No phenotypic effects are seen when wrapperScer\UAS.cNa is expressed using Scer\GAL4unspecified either on all muscles or in all photoreceptor neurons in the developing eye.

      (Noordermeer et al., 1998)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescues

      wrapperUAS.cNa/Scer\GAL4wrapper.CH321-61P08 rescues wrapperR175

      (Banerjee et al., 2017)
      Comments

      Expression of wrapperScer\UAS.cNa under the control of Scer\GAL4wrapper.CH321-61P08 rescues the near complete embryonic lethality of wrapperR175 homozygous mutants - the rescued embryos display larval hatching and adult eclosion rates that are comparable to wild-type.

      (Banerjee et al., 2017)
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      wrapperScer\UAS.cNa
      wrapperUAS.cNa
      Name Synonyms
      Saccharomyces cerevisiae UAS construct a of Noordermeer
      (Noordermeer et al., 1998)
      Secondary FlyBase IDs
        References (4)