FB2025_01 , released February 20, 2025
Allele: Dmel\capsID.UAS
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General Information
Symbol
Dmel\capsID.UAS
Species
D. melanogaster
Name
FlyBase ID
FBal0125100
Feature type
allele
Associated gene
Dmel\caps
Associated Insertion(s)
Carried in Construct
P{UAS-caps.ID}
Also Known As
UAS-CapsDN
Key Links
Transgenic product class
inframe_deletion
(Taniguchi et al., 2000)
Mutagen
Nature of the Allele
Transgenic product class
inframe_deletion
(Taniguchi et al., 2000)
Mutagen
in vitro construct
(Taniguchi et al., 2000)
Progenitor genotype
Carried in construct
P{UAS-caps.ID}
Cytology
Description

UASt regulatory sequences drive expression of caps lacking the intracellular domain (encodes the amino terminal 470 amino acids of caps).

(Taniguchi et al., 2000)
Allele components
Component
Use(s)
Regulatory region(s)
UASt
Encoded product / tool
caps
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 1 )
      Disease
      Interaction
      References
      ameliorates  carcinoma
      modeled by EgfrUAS.cBa, psqKK111691
      (Fereres et al., 2019)
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Ectopic expression of capsID.Scer\UAS, a construct lacking the intracellular part, in the developing eye, under the control of Scer\GAL4GMR.PF, display a mild R7 stopping phenotype.

      Expression of capsID.Scer\UAS in both R7 and R8 photoreceptors, under the control of Scer\GAL4sev.PM181, generates a strong R7 axon stopping phenotype.

      (Berger-Müller et al., 2013)

      Expression of capsID.Scer\UAS in ventral muscle 12 causes synaptic terminal defects. In contrast, expression of capsID.Scer\UAS with Scer\GAL4elav.PLu in motoneurons does not lead to synaptic terminal abnormalities.

      (Kohsaka and Nose, 2009)

      Embryos that express capsID.Scer\UAS under the control of Scer\GAL4twi.PG show normal development of the tracheal system.

      (Krause et al., 2006)

      Third instar larvae expressing capsID.Scer\UAS under the control of Scer\GAL4elav.PLu at 29oC show defects in the trajectory of the motorneurons that innervate muscle 12 in 19% of hemisegments. Expression of capsID.Scer\UAS under the control of Scer\GAL4how-24B does not result in an increased frequency of the terminals of motorneurons that normally innervate muscle 12 forming ectopic synapses on muscle 13.

      (Taniguchi et al., 2000)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Enhancer of
      Suppressor of
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      All larvae co-expressing psqKK111691 and EgfrUAS.cBa under the control of Scer\GAL4ap-md544 during larval stages (using Gal80[ts] for the temporal regulation of expression) wing discs tumors, associated with higher numbers of myoblasts. These phenotypes are partially suppressed by the co-expression of capsID.UAS.

      (Fereres et al., 2019)

      Expression of capsID.Scer\UAS under the control of Scer\GAL4twi.PG enhances the severity of the dorsal trunk defects of trn28.4 embryos.

      (Krause et al., 2006)

      capsID.Scer\UAS suppresses the loss of laterally located somatic clones of salmScer\UAS.cdCa; Scer\GAL4Act5C.PP cells in late third instar wing discs.

      (Milan et al., 2002)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      capsID.Scer\UAS
      capsID.UAS
      Name Synonyms
      Secondary FlyBase IDs
        References (9)