FB2025_01 , released February 20, 2025
Allele: Dmel\aubUASp.mGFP6
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General Information
Symbol
Dmel\aubUASp.mGFP6
Species
D. melanogaster
Name
FlyBase ID
FBal0126452
Feature type
allele
Associated gene
Dmel\aub
Associated Insertion(s)
Carried in Construct
P{UASp-GFP-aub.H}
Also Known As
UAS-gfp-aub, UASp-GFP-Aub, UAS-aub-gfp, gfp-aub
Key Links
Transgenic product class
cDNA
(Harris and Macdonald, 2001)
wild_type
(Harris and Macdonald, 2001)
Mutagen
Nature of the Allele
Transgenic product class
cDNA
(Harris and Macdonald, 2001)
wild_type
(Harris and Macdonald, 2001)
Mutagen
in vitro construct
(Harris and Macdonald, 2001)
Progenitor genotype
Carried in construct
P{UASp-GFP-aub.H}
Cytology
Description

UASp regulatory sequences drive expression of an aub cDNA (EST LD23087) tagged at the N-terminal end with mGFP6.

(Harris and Macdonald, 2001)
Allele components
Component
Use(s)
Regulatory region(s)
UASp
Encoded product / tool
aub
Tagged with
mGFP6
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 1 )
      Disease
      Interaction
      References
      exacerbates  amyotrophic lateral sclerosis type 6
      modeled by cazVDRC.cUa
      (Wakisaka et al., 2019)
      modeled by cazHMS00790
      (Wakisaka et al., 2019)
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Expression of aubUASp.mGFP6 under the control of Scer\GAL4tj-NP1624 does not lead to any obvious ovary/egg chamber phenotype.

      (Coux et al., 2018)

      Expression of aubScer\UAS.P\T.T:Avic\GFP-m6 under the control of Scer\GAL4nos.UTR.T:Hsim\VP16 does not induce embryonic lethality or dorsal appendages defects in embryos.

      (Barckmann et al., 2015)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescues

      Scer\GAL4VP16.nanos.UTR/aubUASp.mGFP6 rescues aubunspecified

      (Harris and Macdonald, 2001)
      Partially rescues

      Scer\GAL4VP16.nanos.UTR/aubUASp.mGFP6 partially rescues aubHN2/aubQC42

      (Barckmann et al., 2015)
      Comments

      The maternal effect embryonic lethality and dorsal appendages fusion phenotypes characteristic for embryos from aubHN2/aubQC42 mothers are partially rescued by expression of aubScer\UAS.P\T.T:Avic\GFP-m6 under the control of Scer\GAL4nos.UTR.T:Hsim\VP16 in the embryos.

      (Barckmann et al., 2015)
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      aubScer\UAS.P\T.T:Avic\GFP-m6
      aubUASp.mGFP6
      Name Synonyms
      Secondary FlyBase IDs
        References (23)