|Feature type||allele||Associated gene||Dmel\Sox15|
|Map ( GBrowse )||
|Allele class||amorphic allele - genetic evidence|
What does this section display?
This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms).
What does this section not display?
This section does not currently display links that were removed or gene model changes.
Click the icon below to subscribe to this FlyBase record and receive updates automatically through your feed reader.
|All updates||Click here to see a list of all updates to this record from FB2010_08 and on.|
|Nature of the Allele|
|Mutations Mapped to the Genome|
|Associated Sequence Data|
|Nature of the lesion|
Insertion within the first intron.
|Caused by insertion|
|Phenotype Manifest In|
Most homozygous Sox15[KG09145] flies die as pharate adults. The homozygous Sox15[KG09145] escapers are weak and display held-out wings. The held-out-wing phenotype is the result of abnormalities in proximal hinge structures, such as the sclerites, the alula and the costa. Sox15[KG09145] mutant third instar larval wing imaginal discs show hinge overgrowth that causes extra folds both dorsally and ventrally. There is an increase in cell proliferation in the hinge region of Sox15[KG09145] mutant L3 wing imaginal discs relative to the wild-type. The rate of apoptotic cell death is also increased in Sox15[KG09145] mutant wing discs in the hinge region. The wing pouch and body wall regions appear unaffected in Sox15[KG09145] mutant third instar larval wing imaginal discs.
Sox15KG09145 is an enhancer of decreased cell number | recessive | third instar larval stage phenotype of wgspd-fg
|Phenotype Manifest In|
In wg[spd-fg], Sox15[KG09145] double mutant third instar larval wing imaginal discs, the distal hinge region is reduced in size compared to either single mutant. The rate of hinge-specific apoptosis is similar in wg[spd-fg], Sox15[KG09145] double mutant and Sox15[KG09145] single mutant L3 wing discs.
|Complementation & Rescue Data|
|Stocks ( 2 )|
|Notes on Origin|
|External Crossreferences & Linkouts|
|Synonyms & Secondary IDs ( 2 )|
|Secondary FlyBase IDs|
|References ( 5 )|
|Personal communication to FlyBase|