FB2025_01 , released February 20, 2025
Allele: Dmel\Act5CG0245
Open Close
General Information
Symbol
Dmel\Act5CG0245
Species
D. melanogaster
Name
FlyBase ID
FBal0152795
Feature type
allele
Associated gene
Dmel\Act5C
Associated Insertion(s)
P{lacW}Act5CG0245
Carried in Construct
Key Links
Genomic Maps

Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
P-element activity
(Schäfer et al., 1999.6.15)
Progenitor genotype
Associated Insertion(s)
P{lacW}Act5CG0245
Cytology
Description
Allele components
Component
Use(s)
Inserted element
P{lacW}
Encoded product / tool
lacZ
Tagged with
Tag:NLS(P)
Mutations Mapped to the Genome
Curation Data
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
AJ426704
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Mutants die at the L3 moult.

      (Peter et al., 2002)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Enhancer of
      Statement
      Reference

      Act5CG0245/Act5C[+] is an enhancer of retina phenotype of eys1, prom[+]/prom1

      (Nie et al., 2014)
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      One copy of both eys1 and prom1 results in a partial failure to form a continuous open inter-rhabdomeral space (retinal lumen), exhibited by the presence of juxtaposed rhabdomeres. This phenotype is significantly enhanced by one copy of either Df(1)ED6829 or Act5CG0245.

      (Nie et al., 2014)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      Comments
      Comments

      P{lacW} not verified as causing the lethality.

      (Schäfer et al., 1999.6.15)
      External Crossreferences and Linkouts ( 1 )
      Crossreferences
      GenBank Nucleotide - A collection of sequences from several sources, including GenBank, RefSeq, TPA, and PDB.
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      Act5CG0245
      (Nie et al., 2014)
      l(1)G0245
      (Peter et al., 2002)
      l(1)G0245G0245
      (Schäfer et al., 1999.6.15)
      Name Synonyms
      Secondary FlyBase IDs
      • FBal0098148
      References (4)