Allele Dmel\jeb^weli

General Information
Symbol	Dmel\jeb^weli	Species	D. melanogaster
Name	welville	FlyBase ID	FBal0159133
Feature type	allele	Associated gene	Dmel\jeb

Allele class
Mutagen	ethyl methanesulfonate
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
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FB2013_03
FB2013_02
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Nature of the Allele
Allele class
Mutagen	ethyl methanesulfonate (Stute et al., 2004)
Mutations Mapped to the Genome

Type Location Additional Notes References
Associated Sequence Data
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name

UniProtKB/Swiss-Prot
UniProtKB/TrEMBL

Progenitor genotype
Nature of the lesion	Statement Reference
Cytology
Phenotypic Data
Phenotypic Class

Phenotype Manifest In
	circular visceral muscle primordium (Wolfstetter et al., 2009) fusion competent cell & visceral muscle primordium (Stute et al., 2004) muscle founder cell & circular visceral muscle primordium (Stute et al., 2004)
Detailed Description
	Statement Reference Mutant embryos lack all circular visceral founder cells, but show normal early endoderm migration. (Wolfstetter et al., 2009) Morphological and marker analyses indicate that stage 11 jeb^weli homozygous embryos lack muscle founder cells in their circular visceral mesoderm. The remaining cells in the visceral mesoderm differentiate as fusion competent myoblasts and express genes that are characteristic for this differentiated cell type. (Stute et al., 2004)
External Data
Linkouts
Interactions
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement Reference
Xenogenetic Interactions
Statement Reference
Complementation & Rescue Data
Fails to complement	jeb^SH0422 (Bazigou et al., 2007)
Comments
Stocks ( 0 )

Notes on Origin
Discoverer

External Crossreferences & Linkouts
Other Crossreferences

Linkouts

Synonyms & Secondary IDs ( 3 )
Reported As
Symbol Synonym	jeb^weli (Bazigou et al., 2007, Wolfstetter et al., 2009)
Name Synonym	jelly belly^welville (Wolfstetter et al., 2009) welville
Secondary FlyBase IDs

References ( 3 )
Research paper	Wolfstetter et al., 2009, Mech. Dev. 126(8-9): 721--736 Fusion of circular and longitudinal muscles in Drosophila is independent of the endoderm but further visceral muscle differentiation requires a close contact between mesoderm and endoderm. [FBrf0208570] Stute et al., 2004, Development 131(4): 743--754 Myoblast determination in the somatic and visceral mesoderm depends on Notch signalling as well as on milliways (mili[Alk]) as receptor for Jeb signalling. [FBrf0174588]
Supplementary material	Bazigou et al., 2007, Cell 128(5): Supplemental Data. Anterograde Jelly belly and Alk receptor tyrosine kinase signaling mediates retinal axon targeting in Drosophila. [FBrf0199314]

Allele Dmel\jebweli

Allele Dmel\jeb^weli