FlyBase Allele Report: Dmel\sra[05203]

General Information

Symbol

Dmel\sra⁰⁵²⁰³

Species

D. melanogaster

Name

FlyBase ID

FBal0196942

Feature type

allele

Associated gene

Dmel\sra

Associated Insertion(s)

P{PZ}sra⁰⁵²⁰³

Carried in Construct

Also Known As

l(3)05203

Key Links

Allele class

loss of function allele

Mutagen

P-element activity

Nature of the Allele

Allele class

loss of function allele

(Horner, 2006)

Mutagen

P-element activity

Progenitor genotype

Associated Insertion(s)

P{PZ}sra⁰⁵²⁰³

Cytology

Description

Allele components

Component

Use(s)

Inserted element

P{PZ}

enhancer trap

Encoded product / tool

lacZ

reporter enzyme

Tagged with

Tag:NLS(P)

nuclear protein localization tag

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal meiotic cell cycle | female | germline clone

(Horner et al., 2006)

female sterile (with Df(3R)sbd45)

(Horner, 2006)

female sterile | germline clone

(Horner, 2006)

lethal

(Horner, 2006)

lethal | embryonic stage | maternal effect

(Perrimon et al., 1996)

lethal | larval stage | recessive

(Perrimon et al., 1996)

lethal | recessive

(Spradling et al., 1999)

viable

(Horner et al., 2006)

Phenotype Manifest In

embryonic/first instar larval cuticle | maternal effect

(Perrimon et al., 1996)

meiotic anaphase I | female | germline clone

(Horner et al., 2006)

Detailed Description

Statement

Reference

Eggs produced by sra⁰⁵²⁰³ mutant germline clones in mother heterozygous for sra⁰⁵²⁰³ show anaphase I arrest.

(Horner et al., 2006)

Germline clones produce normal eggs with no cuticle development.

(Perrimon et al., 1996)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Fails to complement

sra⁰⁸⁷⁰⁵

(BDGP Project Members, 1994-1999)

sra⁰⁸²³⁵

(BDGP Project Members, 1994-1999)

sra⁰⁷⁶³⁶

(BDGP Project Members, 1994-1999)

sra⁰⁵⁷⁰²

(BDGP Project Members, 1994-1999)

sra⁰⁰⁹³⁴

(BDGP Project Members, 1994-1999)

Rescued by

sra⁰⁵²⁰³ is rescued by sra^cHa

(Horner, 2006)

Comments

Images (0)

Mutant

Wild-type

Stocks (1)

Bloomington

11652

ry⁵⁰⁶ P{PZ}sra⁰⁵²⁰³/TM3, ry^RK Sb¹ Ser¹

Notes on Origin

Discoverer

A. Spradling.

Comments

Complements: tara⁰³⁸⁸¹. Complements: tara⁰⁵⁴⁷². Complements: l(3)L1820^L1820. Complements: l(3)j1A1^j1A1. Complements: srp^neo45. Complements: l(3)neo46¹. Complements: l(3)neo47¹. Complements: gish⁰⁴⁸⁹⁵.

(BDGP Project Members, 1994-1999)

Revertants demonstrate the P{PZ} insertion causes the female sterile phenotype.

(Horner, 2006)

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (4)

Reported As

Symbol Synonym

l(3)05203

(McClure and Schubiger, 2008, Spradling et al., 1999)

l(3)05203⁰⁵²⁰³

sra⁰⁵²⁰³

(Horner et al., 2006)

sra¹⁶⁵²

(Horner, 2006)

Name Synonyms

Secondary FlyBase IDs

FBal0009531
FBal0194827

References (10)

Report Sections

Open Close