Allele Dmel\Ir76a^Scer\UAS.cBa

General Information
Symbol	Dmel\Ir76a^Scer\UAS.cBa	Species	D. melanogaster
Name	Saccharomyces cerevisiae UAS construct a of Benton	FlyBase ID	FBal0220386
Feature type	allele	Associated gene	Dmel\Ir76a

Allele class
Mutagen	in vitro construct - regulatory fusion
Recent Updates
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FB2013_03
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Nature of the Allele
Allele class
Mutagen	in vitro construct - regulatory fusion (Benton et al., 2009)
Mutations Mapped to the Genome

Type Location Additional Notes References
Associated Sequence Data
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name

UniProtKB/Swiss-Prot
UniProtKB/TrEMBL

Progenitor genotype
Nature of the lesion	Statement Reference Scer\UAS regulatory sequences drive expression of the predicted full length Ir76a open reading frame. (Benton et al., 2009)
Carried in construct	P{UAS-Ir76a.B} (Benton et al., 2009, Benton et al., 2009, Abuin et al., 2011)
Cytology
Phenotypic Data
Phenotypic Class

Phenotype Manifest In

Detailed Description
	Statement Reference Expression of Ir76a[Scer\UAS.cBa] under the control of Scer\GAL4[Or35a.PF] does not result in a strong olfactory response to phenylacetaldehyde in the ac3 sensilla (this is comparable to the lack of response seen in ac3 sensilla in control flies). (Benton et al., 2009)
External Data
Linkouts
Interactions
	Show the genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Other
Statement Reference Ir25a^Scer\UAS.cAa, Ir76a^Scer\UAS.cBa, Ir76b^Scer\UAS.cAa, Scer\GAL4^Or22a.7.717 has neurophysiology defective phenotype (Abuin et al., 2011)
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement Reference Neurons co-expressing Ir25a[Scer\UAS.cAa] and Ir76a[Scer\UAS.cBa] driven by Scer\GAL4[Or22a.7.717] do not respond to phenylethyl amine above basal solvent-evoked activity. Neurons co-expressing Ir76a[Scer\UAS.cBa] and Ir76b[Scer\UAS.cAa] driven by Scer\GAL4[Or22a.7.717] do not respond to phenylethyl amine above basal solvent-evoked activity. Neurons co-expressing Ir25a[Scer\UAS.cAa] with Ir76a[Scer\UAS.cBa] and Ir76b[Scer\UAS.cAa] driven by Scer\GAL4[Or22a.7.717] show a robust response to phenylethyl amine. (Abuin et al., 2011)
Xenogenetic Interactions
Statement Reference
Complementation & Rescue Data
Comments
Stocks ( 1 )
Bloomington	41738 w^*; P{UAS-Ir76a.B}294.3; TM2/TM6B, Tb¹
Notes on Origin
Discoverer

External Crossreferences & Linkouts
Other Crossreferences

Linkouts

Synonyms & Secondary IDs ( 2 )
Reported As
Symbol Synonym	Ir76a^Scer\UAS.cBa
Name Synonym	Saccharomyces cerevisiae UAS construct a of Benton
Secondary FlyBase IDs

References ( 3 )
Research paper	Abuin et al., 2011, Neuron 69(1): 44--60 Functional architecture of olfactory ionotropic glutamate receptors. [FBrf0212725] Benton et al., 2009, Cell 136(1): 149--162 Variant ionotropic glutamate receptors as chemosensory receptors in Drosophila. [FBrf0206496]
Supplementary material	Benton et al., 2009, Cell 136(1): Supplemental Experimental Procedures. [FBrf0207607]

Allele Dmel\Ir76aScer\UAS.cBa

Allele Dmel\Ir76a^Scer\UAS.cBa