FB2025_01 , released February 20, 2025
Allele: Dmel\Ir76aUAS.cBa
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General Information
Symbol
Dmel\Ir76aUAS.cBa
Species
D. melanogaster
Name
Saccharomyces cerevisiae UAS construct a of Benton
FlyBase ID
FBal0220386
Feature type
allele
Associated gene
Dmel\Ir76a
Associated Insertion(s)
Carried in Construct
P{UAS-Ir76a.B}
Also Known As
UAS-IR76a
Key Links
Transgenic product class
wild_type
(Benton et al., 2009)
Mutagen
Nature of the Allele
Transgenic product class
wild_type
(Benton et al., 2009)
Mutagen
in vitro construct
(Benton et al., 2009)
Progenitor genotype
Carried in construct
P{UAS-Ir76a.B}
Cytology
Description

UASt regulatory sequences drive expression of the predicted full length Ir76a open reading frame.

(Benton et al., 2009)
Allele components
Component
Use(s)
Regulatory region(s)
UASt
Encoded product / tool
Ir76a
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Expression of Ir76aScer\UAS.cBa under the control of Scer\GAL4Or35a.PF does not result in a strong olfactory response to phenylacetaldehyde in the ac3 sensilla (this is comparable to the lack of response seen in ac3 sensilla in control flies).

      (Benton et al., 2009)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Neurons co-expressing Ir25aScer\UAS.cAa and Ir76aScer\UAS.cBa driven by Scer\GAL4Or22a.7.717 do not respond to phenylethyl amine above basal solvent-evoked activity.

      Neurons co-expressing Ir76aScer\UAS.cBa and Ir76bScer\UAS.cAa driven by Scer\GAL4Or22a.7.717 do not respond to phenylethyl amine above basal solvent-evoked activity.

      Neurons co-expressing Ir25aScer\UAS.cAa with Ir76aScer\UAS.cBa and Ir76bScer\UAS.cAa driven by Scer\GAL4Or22a.7.717 show a robust response to phenylethyl amine.

      (Abuin et al., 2011)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      Ir76aScer\UAS.cBa
      Ir76aUAS.cBa
      Name Synonyms
      Saccharomyces cerevisiae UAS construct a of Benton
      Secondary FlyBase IDs
        References (3)