FlyBase Allele Report: Dmel\Pfk[KK101887]

General Information

Symbol

Dmel\Pfk^KK101887

Species

D. melanogaster

Name

FlyBase ID

FBal0231545

Feature type

allele

Associated gene

Dmel\Pfk

Associated Insertion(s)

Carried in Construct

P{KK101887}

Also Known As

UAS-Pfk^RNAi

Key Links

Genomic Maps

JBrowse

Transgenic product class

RNAi_reagent

(Keleman et al., 2009.8.5)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

RNAi_reagent

(Keleman et al., 2009.8.5)

Mutagen

in vitro construct

(Keleman et al., 2009.8.5)

Progenitor genotype

Carried in construct

P{KK101887}

Cytology

Description

UASt regulatory sequences drive expression of an inverted repeat.

(Keleman et al., 2009.8.5)

Allele components

Component

Use(s)

Regulatory region(s)

UASt

binary expression system - regulatory region

Encoded product / tool

dsRNA-KK101887

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

decreased efficacy of long-term memory | adult stage, with Scer\GAL4^GMR54H02

(Rabah et al., 2023)

decreased efficacy of medium-term memory | adult stage, with Scer\GAL4^GMR54H02

(Rabah et al., 2023)

Phenotype Manifest In

embryonic myoblast, with Scer\GAL4^kirre.PU

(Tixier et al., 2013)

larval somatic muscle cell, with Scer\GAL4^kirre.PU

(Tixier et al., 2013)

Detailed Description

Statement

Reference

Embryos expressing Pfk^KK101887 under the control of Scer\GAL4^kirre.PU have thinner muscles than normal and unfused myoblasts are present.

(Tixier et al., 2013)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Suppressor of

Statement

Reference

Pfk^KK101887, Scer\GAL4^repo is a suppressor | partially of abnormal wound healing | larval stage phenotype of Pi3K92E^{UAS.Tag:MYC,Tag:PM(hKRAS)}, Scer\GAL4^repo, btl::Egfr^λ.UAS

(Li et al., 2020)

Pfk^KK101887, Scer\GAL4^repo is a suppressor | partially of abnormal wound healing | larval stage phenotype of Myc^UAS.cZa, Scer\GAL4^repo

(Li et al., 2020)

Other

Statement

Reference

Alat^GD9174, Pfk^KK101887, Scer\GAL4^GMR54H02 has decreased efficacy of medium-term memory | adult stage phenotype

(Rabah et al., 2023)

Phenotype Manifest In

Enhancer of

Statement

Reference

Pfk^KK101887, Scer\GAL4^drm.7.1 is an enhancer of terminal tracheal cell | larval stage phenotype of Scer\GAL4^drm.7.1, trc^GL01127

(Hudson et al., 2023)

Suppressor of

Statement

Reference

Pfk^KK101887, Scer\GAL4^repo is a suppressor | partially of larval multidendritic class IV neuron phenotype of Pi3K92E^{UAS.Tag:MYC,Tag:PM(hKRAS)}, Scer\GAL4^repo, btl::Egfr^λ.UAS

(Li et al., 2020)

Pfk^KK101887, Scer\GAL4^repo is a suppressor | partially of larval multidendritic class IV neuron phenotype of Myc^UAS.cZa, Scer\GAL4^repo

(Li et al., 2020)

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (1)

VDRC

v105666

P{KK101887}VIE-260B

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

Pfk^KK101887

Pfk^RNAi

(Bonnay et al., 2020)

Name Synonyms

Secondary FlyBase IDs

References (10)

Report Sections

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