FlyBase Allele Report: Dmel\CHOp24[KK107384]

General Information

Symbol

Dmel\CHOp24^KK107384

Species

D. melanogaster

Name

FlyBase ID

FBal0234902

Feature type

allele

Associated gene

Dmel\CHOp24

Associated Insertion(s)

Carried in Construct

P{KK107384}

Key Links

Genomic Maps

JBrowse

Transgenic product class

RNAi_reagent

(Keleman et al., 2009.8.5)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

RNAi_reagent

(Keleman et al., 2009.8.5)

Mutagen

in vitro construct

(Keleman et al., 2009.8.5)

Progenitor genotype

Carried in construct

P{KK107384}

Cytology

Description

UASt regulatory sequences drive expression of an inverted repeat.

(Keleman et al., 2009.8.5)

Allele components

Component

Use(s)

Regulatory region(s)

UASt

binary expression system - regulatory region

Encoded product / tool

dsRNA-KK107384

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

female semi-sterile, with Scer\GAL4^Act5C.PI

(Saleem et al., 2012)

lethal, with Scer\GAL4^Act5C.PI

(Saleem et al., 2012)

viable, with Scer\GAL4^Act5C.PI

(Saleem et al., 2012)

Phenotype Manifest In

wing margin, with Scer\GAL4^hh.PU

(Port et al., 2011)

wing margin | somatic clone, with Scer\GAL4^Act5C.PI

(Port et al., 2011)

Detailed Description

Statement

Reference

Flies expressing CHOp24^KK107384 during adulthood under the control of Scer\GAL4^Act5C.PI and Scer\GAL80^ts.αTub84B are viable but female flies lay fewer egg per day compared to controls. Male fertility is unaffected.

(Saleem et al., 2012)

Expression of CHOp24^KK107384 using Scer\GAL4^hh.PU leads to loss of posterior wing margin tissue.

Expression of CHOp24^KK107384 in clones using Scer\GAL4^Act5C.PI frequently leads to loss of posterior wing margin tissue.

(Port et al., 2011)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

Suppressor of

Statement

Reference

CHOp24^KK107384, Scer\GAL4^ey.PU, Scer\GAL4^GMR.PU is a suppressor of eye phenotype of wg^hs.2sev

(Port et al., 2011)

Additional Comments

Genetic Interactions

Statement

Reference

wg^hs.2sev rough eyes are suppressed when CHOp24^KK107384 is expressed using both Scer\GAL4^ey.PU and Scer\GAL4^GMR.PU.

(Port et al., 2011)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (1)

VDRC

v100274

P{KK107384}VIE-260B

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (1)

Reported As

Symbol Synonym

CHOp24^KK107384

Name Synonyms

Secondary FlyBase IDs

References (3)

Report Sections

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