FlyBase Allele Report: Dmel\Marcal1[HMS00587]

General Information

Symbol

Dmel\Marcal1^HMS00587

Species

D. melanogaster

Name

FlyBase ID

FBal0257273

Feature type

allele

Associated gene

Dmel\Marcal1

Associated Insertion(s)

Carried in Construct

P{TRiP.HMS00587}

Key Links

Genomic Maps

JBrowse

Transgenic product class

RNAi_reagent

(Ni et al., 2010.12.1)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

RNAi_reagent

(Ni et al., 2010.12.1)

Mutagen

in vitro construct

(Ni et al., 2010.12.1)

Progenitor genotype

Carried in construct

P{TRiP.HMS00587}

Cytology

Description

UAS regulatory sequences drive expression of a short inverted repeat.

(Ni et al., 2010.12.1)

Allele components

Component

Use(s)

Regulatory region(s)

UAS

binary expression system - regulatory region

Encoded product / tool

dsRNA-HMS00587

Also carries

loxP

recombinase target site

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

Phenotype Manifest In

adult pericardial cell, with Scer\GAL4^Ugt36A1.PK

(Fu et al., 2017)

Detailed Description

Statement

Reference

Adult flies expressing Marcal1^HMS00587 under the control of Scer\GAL4^Dot.PK display nephrocyte functional defects (measured by uptake assays) but their adult lifespan is comparable to controls.

(Fu et al., 2017)

Expression of Marcal1^HMS00587 under the control of Scer\GAL4^bbg-C96 does not result in any obvious wing phenotype.

(Ellis et al., 2015)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Suppressor of

Statement

Reference

Marcal1^HMS00587, Scer\GAL4^bbg-C96 is a suppressor of visible phenotype of Scer\GAL4^bbg-C96, dom^RNAi.Sym.UAS

(Ellis et al., 2015)

Phenotype Manifest In

Suppressor of

Statement

Reference

Marcal1^HMS00587, Scer\GAL4^bbg-C96 is a suppressor of wing phenotype of Scer\GAL4^bbg-C96, dom^RNAi.Sym.UAS

(Ellis et al., 2015)

Additional Comments

Genetic Interactions

Statement

Reference

Co-expression of Marcal1^HMS00587 suppresses the wing nicking phenotype of flies expressing dom^{dsRNA.Sym.Scer\UAS} under the control of Scer\GAL4^bbg-C96.

(Ellis et al., 2015)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (2)

Bloomington

33709