FlyBase Allele Report: Dmel\Tep1[HMS00641]

General Information

Symbol

Dmel\Tep1^HMS00641

Species

D. melanogaster

Name

FlyBase ID

FBal0257325

Feature type

allele

Associated gene

Dmel\Tep1

Associated Insertion(s)

Carried in Construct

P{TRiP.HMS00641}

Key Links

Genomic Maps

JBrowse

Transgenic product class

RNAi_reagent

(Ni et al., 2010.12.1)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

RNAi_reagent

(Ni et al., 2010.12.1)

Mutagen

in vitro construct

(Ni et al., 2010.12.1)

Progenitor genotype

Carried in construct

P{TRiP.HMS00641}

Cytology

Description

UAS regulatory sequences drive expression of a short inverted repeat.

(Ni et al., 2010.12.1)

Allele components

Component

Use(s)

Regulatory region(s)

UAS

binary expression system - regulatory region

Encoded product / tool

dsRNA-HMS00641

Also carries

loxP

recombinase target site

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 1 )

Disease

Interaction

References

ameliorates high grade glioma

modeled by Pten^{RNAi.Exel.UAS}, Ras85D^V12.cUa.UAS

(Gangwani et al., 2020)

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

Phenotype Manifest In

Detailed Description

Statement

Reference

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Suppressor of

Statement

Reference

Tep1^HMS00641, Scer\GAL4^repo.PU is a suppressor | partially of increased occurrence of cell division | third instar larval stage phenotype of Pten^{RNAi.Exel.UAS}, Ras85D^V12.cUa.UAS, Scer\GAL4^repo.PU

(Gangwani et al., 2020)

Tep1^HMS00641, Scer\GAL4^repo.PU is a suppressor | partially of neoplasia | third instar larval stage phenotype of Pten^{RNAi.Exel.UAS}, Ras85D^V12.cUa.UAS, Scer\GAL4^repo.PU

(Gangwani et al., 2020)

Tep1^HMS00641, Scer\GAL4^repo.PU is a suppressor | partially of abnormal neuroanatomy | third instar larval stage phenotype of Pten^{RNAi.Exel.UAS}, Ras85D^V12.cUa.UAS, Scer\GAL4^repo.PU

(Gangwani et al., 2020)

Tep1^HMS00641, Scer\GAL4^repo.PU is a suppressor of increased cell number | third instar larval stage phenotype of Pten^{RNAi.Exel.UAS}, Ras85D^V12.cUa.UAS, Scer\GAL4^repo.PU

(Gangwani et al., 2020)

yki^HMS00041/Tep1^HMS00641, Scer\GAL4^repo.PU is a suppressor of increased cell number | third instar larval stage phenotype of Pten^{RNAi.Exel.UAS}, Ras85D^V12.cUa.UAS, Scer\GAL4^repo.PU

(Gangwani et al., 2020)

yki^HMS00041/Tep1^HMS00641, Scer\GAL4^repo.PU is a suppressor | partially of abnormal neuroanatomy | third instar larval stage phenotype of Pten^{RNAi.Exel.UAS}, Ras85D^V12.cUa.UAS, Scer\GAL4^repo.PU

(Gangwani et al., 2020)

yki^HMS00041/Tep1^HMS00641, Scer\GAL4^repo.PU is a suppressor | partially of neoplasia | third instar larval stage phenotype of Pten^{RNAi.Exel.UAS}, Ras85D^V12.cUa.UAS, Scer\GAL4^repo.PU

(Gangwani et al., 2020)

Phenotype Manifest In

Suppressor of

Statement

Reference

Tep1^HMS00641, Scer\GAL4^repo.PU is a suppressor | partially of larval central brain | third instar larval stage phenotype of Pten^{RNAi.Exel.UAS}, Ras85D^V12.cUa.UAS, Scer\GAL4^repo.PU

(Gangwani et al., 2020)

Tep1^HMS00641, Scer\GAL4^repo.PU is a suppressor of neuroblast | increased number | third instar larval stage phenotype of Pten^{RNAi.Exel.UAS}, Ras85D^V12.cUa.UAS, Scer\GAL4^repo.PU

(Gangwani et al., 2020)

yki^HMS00041/Tep1^HMS00641, Scer\GAL4^repo.PU is a suppressor of neuroblast | increased number | third instar larval stage phenotype of Pten^{RNAi.Exel.UAS}, Ras85D^V12.cUa.UAS, Scer\GAL4^repo.PU

(Gangwani et al., 2020)

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (2)

Bloomington

32856

y¹ sc^* v¹ sev²¹; P{TRiP.HMS00641}attP2

NIG-Fly

HMS00641

y¹ sc^* v¹ sev²¹; P{TRiP.HMS00641}attP2

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

Tep1^HMS00641

TepI^HMS00641

Name Synonyms

Secondary FlyBase IDs

References (2)

Report Sections

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