FlyBase Allele Report: Dmel\dally[HMS00905]

General Information

Symbol

Dmel\dally^HMS00905

Species

D. melanogaster

Name

FlyBase ID

FBal0257580

Feature type

allele

Associated gene

Dmel\dally

Associated Insertion(s)

Carried in Construct

P{TRiP.HMS00905}

Also Known As

UAS-dally RNAi

Key Links

Genomic Maps

JBrowse

Transgenic product class

RNAi_reagent

(Ni et al., 2010.12.1)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

RNAi_reagent

(Ni et al., 2010.12.1)

Mutagen

in vitro construct

(Ni et al., 2010.12.1)

Progenitor genotype

Carried in construct

P{TRiP.HMS00905}

Cytology

Description

UAS regulatory sequences drive expression of a short inverted repeat.

(Ni et al., 2010.12.1)

Allele components

Component

Use(s)

Regulatory region(s)

UAS

binary expression system - regulatory region

Encoded product / tool

dsRNA-HMS00905

Also carries

loxP

recombinase target site

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

short lived, with Scer\GAL4^Ugt36A1.PK

(Fu et al., 2017)

Phenotype Manifest In

Detailed Description

Statement

Reference

Adulthood-only expression of dally^HMS00905 under the combined control of Scer\GAL4^esg.PU and Gal80[ts] (induced by temperature shift from 18[o]C to 29[o]C) does not have a major effect on the number of presumptive intestinal progenitors (i.e. esg-positive cells) in the adult posterior midgut, as compared to controls.

(Ma et al., 2019)

Adult flies expressing dally^HMS00905 under the control of Scer\GAL4^Dot.PK do not display nephrocyte functional defects (measured by uptake assays) but their adult lifespan is reduced compared to controls.

(Fu et al., 2017)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

NOT Enhancer of

Statement

Reference

dally^HMS00905, Scer\GAL4^Ser.PGF is a non-enhancer of decreased size | adult stage phenotype of Psi^KK101882, Scer\GAL4^Ser.PGF

(Zaytseva et al., 2023)

NOT Suppressor of

Statement

Reference

dally^HMS00905, Scer\GAL4^Ser.PGF is a non-suppressor of decreased size | adult stage phenotype of Psi^KK101882, Scer\GAL4^Ser.PGF

(Zaytseva et al., 2023)

Phenotype Manifest In

NOT Enhancer of

Statement

Reference

dally^HMS00905, Scer\GAL4^Ser.PGF is a non-enhancer of wing posterior compartment phenotype of Psi^KK101882, Scer\GAL4^Ser.PGF

(Zaytseva et al., 2023)

NOT Suppressor of

Statement

Reference

dally^HMS00905, Scer\GAL4^Ser.PGF is a non-suppressor of wing posterior compartment phenotype of Psi^KK101882, Scer\GAL4^Ser.PGF

(Zaytseva et al., 2023)

Additional Comments

Genetic Interactions

Statement

Reference

Adulthood-only co-expression of dlp^HMS00875 and dally^HMS00905 under the combined control of Scer\GAL4^esg.PU and Gal80[ts] (induced by temperature shift from 18[o]C to 29[o]C) does not have a major effect on the number of presumptive intestinal progenitors (i.e. esg-positive cells) in the adult posterior midgut, as compared to controls.

(Ma et al., 2019)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (2)

Bloomington

33952