FB2025_01 , released February 20, 2025
Allele: Dmel\Caf1-180UAS.cSa
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General Information
Symbol
Dmel\Caf1-180UAS.cSa
Species
D. melanogaster
Name
Saccharomyces cerevisiae UAS construct a of Song
FlyBase ID
FBal0267423
Feature type
allele
Associated gene
Dmel\Caf1-180
Associated Insertion(s)
Carried in Construct
P{UAS-Caf1-180.S}
Key Links
Transgenic product class
cDNA
(Song et al., 2007)
wild_type
(Song et al., 2007)
Mutagen
Nature of the Allele
Transgenic product class
cDNA
(Song et al., 2007)
wild_type
(Song et al., 2007)
Mutagen
in vitro construct
(Song et al., 2007)
Progenitor genotype
Carried in construct
P{UAS-Caf1-180.S}
Cytology
Description

UASt regulatory sequences drive expression of a full length Caf1-180 cDNA.

(Song et al., 2007)
Allele components
Component
Use(s)
Regulatory region(s)
UASt
Encoded product / tool
Caf1-180
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Flies expressing Caf1-180Scer\UAS.cSa under the control of Scer\GAL4ey.PH have small eyes compared to wild type. The phenotype is stronger with two copies of the transgene compared with one copy.

      (Wen et al., 2012)

      Eye-specific expression of Caf1-180Scer\UAS.cSa driven by Scer\GAL4ey.PH results in a small-eye phenotype.

      (Song et al., 2007)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      NOT Enhanced by
      Suppressed by
      Phenotype Manifest In
      Suppressed by
      Statement
      Reference

      Caf1-180UAS.cSa, Scer\GAL4ey.PH has eye phenotype, suppressible by BlmUAS.cSa, Scer\GAL4ey.PH

      (Song et al., 2007)

      Caf1-180UAS.cSa, Scer\GAL4ey.PH has eye phenotype, suppressible by asf1UAS.cMa, Scer\GAL4ey.PH

      (Song et al., 2007)

      Caf1-180UAS.cSa, Scer\GAL4ey.PH has eye phenotype, suppressible by mus309[+]/BlmD2

      (Song et al., 2007)

      Caf1-180UAS.cSa, Scer\GAL4ey.PH has eye phenotype, suppressible by asf1[+]/asf11

      (Song et al., 2007)

      Caf1-180UAS.cSa, Scer\GAL4ey.PH has eye phenotype, suppressible by BacA\p35UAS.cHa, Scer\GAL4ey.PH

      (Song et al., 2007)
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Co-expression of Caf1Scer\UAS.cWa does not enhance the small eye phenotype seen when Caf1-180Scer\UAS.cSa is expressed under the control of Scer\GAL4ey.PH.

      (Wen et al., 2012)

      The small-eye phenotype is suppressed in flies co-expressing BlmScer\UAS.cSa with Caf1-180Scer\UAS.cSa under the control of Scer\GAL4ey.PH.

      The small-eye phenotype is suppressed in flies co-expressing asf1Scer\UAS.cMa with Caf1-180Scer\UAS.cSa under the control of Scer\GAL4ey.PH.

      The small-eye phenotype of flies expressing Caf1-180Scer\UAS.cSa under the control of Scer\GAL4ey.PH is suppressed by heterozygous BlmD2.

      The small-eye phenotype of flies expressing Caf1-180Scer\UAS.cSa under the control of Scer\GAL4ey.PH is suppressed by heterozygous asf11.

      (Song et al., 2007)
      Xenogenetic Interactions
      Statement
      Reference

      The small-eye phenotype is suppressed in flies co-expressing BacA\p35Scer\UAS.cHa with Caf1-180Scer\UAS.cSa under the control of Scer\GAL4ey.PH.

      (Song et al., 2007)
      Complementation and Rescue Data
      Rescues

      Caf1-180UAS.cSa rescues Caf1-180270

      (Song et al., 2007)
      Comments

      Ubiquitous expression of Caf1-180Scer\UAS.cSa under the control of Scer\GAL4ptc-559.1 completely rescues the mutant phenotypes associated with Caf1-180270.

      (Song et al., 2007)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (4)
      Reported As
      Symbol Synonym
      Caf1-180Scer\UAS.cSa
      Caf1-180UAS.cSa
      Caf1Scer\UAS.cSa
      Name Synonyms
      Saccharomyces cerevisiae UAS construct a of Song
      Secondary FlyBase IDs
        References (2)