FlyBase Allele Report: Dmel\Rchy1[HMJ22014]

General Information

Symbol

Dmel\Rchy1^HMJ22014

Species

D. melanogaster

Name

FlyBase ID

FBal0300501

Feature type

allele

Associated gene

Dmel\Rchy1

Associated Insertion(s)

Carried in Construct

P{TRiP.HMJ22014}

Key Links

Genomic Maps

JBrowse

Transgenic product class

RNAi_reagent

(Ni et al., 2010.12.1)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

RNAi_reagent

(Ni et al., 2010.12.1)

Mutagen

in vitro construct

(Ni et al., 2010.12.1)

Progenitor genotype

Carried in construct

P{TRiP.HMJ22014}

Cytology

Description

UAS regulatory sequences drive expression of a short inverted repeat.

(Ni et al., 2010.12.1)

Allele components

Component

Use(s)

Regulatory region(s)

UAS

binary expression system - regulatory region

Encoded product / tool

dsRNA-HMJ22014

Also carries

loxP

recombinase target site

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

Phenotype Manifest In

Detailed Description

Statement

Reference

The expression of Rchy1^HMJ22014 under the control of Scer\GAL4^insc-Mz1407 does not significantly affect the number of adult brain glial cells at day 7 post eclosion, as compared to controls.

(Foo et al., 2017)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Suppressor of

Statement

Reference

Scer\GAL4^insc-Mz1407/Rchy1^HMJ22014 is a suppressor of decreased cell number | adult stage phenotype of mir-31a^KO

(Foo et al., 2017)

Scer\GAL4^insc-Mz1407/Rchy1^HMJ22014 is a suppressor of decreased cell number | adult stage phenotype of mir-31a^KO/mir-31a^KO.Gal4

(Foo et al., 2017)

Phenotype Manifest In

Suppressor of

Statement

Reference

Scer\GAL4^insc-Mz1407/Rchy1^HMJ22014 is a suppressor of adult CNS glial cell phenotype of mir-31a^KO

(Foo et al., 2017)

Scer\GAL4^mir-31a/Rchy1^HMJ22014 is a suppressor of adult CNS glial cell phenotype of mir-31a^KO/mir-31a^KO.Gal4

(Foo et al., 2017)

Additional Comments

Genetic Interactions

Statement

Reference

The expression of Rchy1^HMJ22014 under the control of Scer\GAL4^insc-Mz1407 or Scer\GAL4^mir-31a (the intrinsic Gal4 driver of mir-31a^KO.Gal4) suppresses the decreased number of 7 days old adult brain glial cells observed in mir-31a^KO homozygotes or mir-31a^KO/mir-31a^KO.Gal4 transheterozygotes, respectively.