FlyBase Allele Report: Dmel\bsf[SH1181]

General Information

Symbol

Dmel\bsf^SH1181

Species

D. melanogaster

Name

FlyBase ID

FBal0321478

Feature type

allele

Associated gene

Dmel\bsf

Associated Insertion(s)

P{lacW}bsf^SH1181

Carried in Construct

Key Links

Genomic Maps

JBrowse

Allele class

amorphic allele - molecular evidence

Mutagen

P-element activity

Nature of the Allele

Allele class

amorphic allele - molecular evidence

(Jaiswal et al., 2015)

Mutagen

P-element activity

(Oh et al., 2003)

Progenitor genotype

Associated Insertion(s)

P{lacW}bsf^SH1181

Cytology

Description

Allele components

Component

Use(s)

Inserted element

P{lacW}

enhancer trap

Encoded product / tool

lacZ

reporter enzyme

Tagged with

Tag:NLS(P)

nuclear protein localization tag

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

transposable_element_insertion_site

2L:18,452,250..18,452,250 [-]

(Kahsai et al., 2016, FlyBase Curators, 2008-, Geng and MacDonald, 2007, Link et al., 2007, Oh et al., 2003)

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

lethal (with Df(2L)BSC149)

(Kahsai et al., 2016)

lethal (with Df(2L)Exel8038)

(Kahsai et al., 2016)

lethal | recessive

(Oh et al., 2003)

lethal - all die before end of pupal stage

(Jaiswal et al., 2015)

Phenotype Manifest In

Detailed Description

Statement

Reference

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Other

Statement

Reference

Lrpprc2^A, bsf^SH1181 has lethal - all die during embryonic stage phenotype

(Jaiswal et al., 2015)

Phenotype Manifest In

Additional Comments

Genetic Interactions

Statement

Reference

Lrpprc2^A/y;bsf^SH1181/bsf^SH1181 double mutants die as embryos (compared to Lrpprc2^A/Y or bsf^SH1181/bsf^SH1181 mutants showing pupal lethality).

(Jaiswal et al., 2015)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Rescued by

bsf^SH1181 is rescued by Scer\GAL4^unspecified/bsf^UAS.cJa

(Jaiswal et al., 2015)

Comments

Ubiquitous expression (GAL4 unspecified) of bsf^Scer\UAS.cJa rescues pupal lethality in

(Jaiswal et al., 2015)

Images (0)

Mutant

Wild-type

Stocks (1)

Bloomington

29492

w^*; P{lacW}bsf^SH1181 P{neoFRT}40A/CyO

Notes on Origin

Discoverer

Deficiency complementation analysis is consistent with the lethality of the line being associated with the insertion.

(Kahsai et al., 2016)

The lethality of the original insertion chromosome may or may not be caused by this allele.

(FlyBase Curators, 2008-)

Comments

Precise excision of the P{lacW} insertion can revert the lethal phenotype.

(Jaiswal et al., 2015)

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

bsf^SH1181

(Jaiswal et al., 2015, Ryu and Macdonald, 2015)

l(2)SH1181^SH1181

Name Synonyms

Secondary FlyBase IDs

FBal0242900
FBal0143745

References (7)

Report Sections

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