FB2025_01 , released February 20, 2025
Gene Group: PEROXINS
Open Close
General Information
Name
PEROXINS
Species
D. melanogaster
Symbol
PEX
FlyBase ID
FBgg0000461
Date last reviewed
2015-06-24
Number of members
16
Description
Description
Peroxisomes are eukaryotic organelles critical for the metabolism of fatty acids, particularly very-long-chain fatty acids, and other metabolites. The peroxin genes encode proteins required for peroxisome biogenesis. (Adapted from FBrf0209624).
Notes on Group

Several peroxin genes have been found in D.mel by homology to yeast or human genes: Pex23 to yeast Yarrowia lipolytica PEX23 (FBrf0215017), Pex7 and CG13827 to human PEX7 and PEX11C (FBrf0219445 and FBrf0222399), respectively. Their function remains unclear in Drosophila (FBrf0215017 and FBrf0219445).

kis, which was suggested as a potential peroxin by its similarity to Yarrowia lipolytica PEX20 (FBrf0215017), has been removed from the PEROXINs Gene Group as it has been well-characterized as a chromatin remodeling factor (FBrf0222914).

Source Material
The PEROXINS Gene Group has been compiled using the following publication(s): Liu and He, 2024, Faust et al., 2012, Mast et al., 2011, and Chen et al., 2010 .
Key Gene Ontology (GO) terms
Molecular Function
Biological Process
peroxisome organization
Cellular Component
peroxisome
Related Gene Groups
Other related group(s)
PEROXISOMAL TARGETING SYSTEM
Members (16)
For all members:
GO ribbon stack
 molecular functionbiological processcellular component
Gene Symbol
Gene Name
Also Known As
Source Material for Membership
Pex1
Peroxin 1
l(3)70Da, l(3)s4868, l(3)S084807, lethal (3) 70Da, l(3)02402
(Faust et al., 2012, Mast et al., 2011, Chen et al., 2010)
Pex2
Peroxin 2
(Faust et al., 2012, Mast et al., 2011, Chen et al., 2010)
Pex3
Peroxin 3
(Faust et al., 2012, Mast et al., 2011, Chen et al., 2010)
Pex5
Peroxin 5
EG:63B12.5
(Faust et al., 2012, Mast et al., 2011, Chen et al., 2010)
Pex6
Peroxin 6
(Faust et al., 2012, Mast et al., 2011, Chen et al., 2010)
Pex7
Peroxin 7
(Faust et al., 2012)
Pex10
Peroxin 10
(Faust et al., 2012, Mast et al., 2011, Chen et al., 2010)
Pex11ab
Peroxin 11a/b
Pex11, Peroxin 11, PEX11A/B
(Faust et al., 2012, Mast et al., 2011, Chen et al., 2010)
Pex11c
Peroxin 11c
(Faust et al., 2012)
Pex11g
Peroxisomal biogenesis factor 11 gamma
(Liu and He, 2024)
Pex12
Peroxin 12
(Faust et al., 2012, Mast et al., 2011, Chen et al., 2010)
Pex13
Peroxin 13
(Faust et al., 2012, Mast et al., 2011, Chen et al., 2010)
Pex14
Peroxin 14
(Faust et al., 2012, Mast et al., 2011, Chen et al., 2010)
Pex16
Peroxin 16
(Faust et al., 2012, Mast et al., 2011, Chen et al., 2010)
Pex19
Peroxin 19
(Faust et al., 2012, Mast et al., 2011, Chen et al., 2010)
Pex23
Peroxin 23
Cdi11
(Mast et al., 2011)
External Data
Equivalent Group(s)
Other resource(s)
Synonyms and Secondary IDs
Synonym(s)
PEX
PEROXINS
Secondary FlyBase ID(s)
References (5)