Reference Report

Reference
Citation	Ryner, L.C., Goodwin, S.F., Castrillon, D.H., Anand, A., Villella, A., Baker, B.S., Hall, J.C., Taylor, B.J., Wasserman, S.A. (1996). Control of male sexual behavior and sexual orientation in Drosophila by the fruitless gene. Cell 87(6): 1079--1089. (Export to RIS)
FlyBase ID	FBrf0091159
Publication Type	Research paper
PubMed ID	8978612
PubMed Abstract	Sexual orientation and courtship behavior in Drosophila are regulated by fruitless (fru), the first gene in a branch of the sex-determination hierarchy functioning specifically in the central nervous system (CNS). The phenotypes of new fru mutants encompass nearly all aspects of male sexual behavior. Alternative splicing of fru transcripts produces sex-specific proteins belonging to the BTB-ZF family of transcriptional regulators. The sex-specific fru products are produced in only about 500 of the 10(5) neurons that comprise the CNS. The properties of neurons expressing these fru products suggest that fru specifies the fates or activities of neurons that carry out higher order control functions to elicit and coordinate the activities comprising male courtship behavior.
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Language of Publication	English
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Publication Type	Journal
Abbreviation	Cell
Title	Cell
Publication Year	1974-
ISBN/ISSN	0092-8674
Data from Reference
Aberrations (9)
	Df(2R)trix Df(3L)st Df(3R)Cha5 Df(3R)Cha^M5 Df(3R)fru^w24 Df(3R)P14 In(3LR)fru^w27 In(3R)fru T(3;?)fru^w12
Alleles (9)
	Ecol\lacZ^Act79B.PCS fru^0-1 fru¹ fru³ fru⁴ fru^w12 fru^w27 tra2^B tra¹
Constructs (1)
	P{Act79B-lacZ.CS}
Genes (5)
	Ecol\lacZ fru gl tra tra2
Insertions (3)
	P{PZ}fru³ P{PZ}fru⁴ P{wA^R}fru^0-1