FlyBase Aberration Report: Dmel\Df(1)D34

General Information

Symbol

Df(1)D34

Species

D. melanogaster

Name

FlyBase ID

FBab0000366

Feature type

chromosomal_deletion

Also Known As

Df(1)LD34, Df(1)l^D34

Computed Breakpoints include

14C6-14C8;14C8-14D1

Features within 14C6--14D1

Sequence coordinates

Member of large scale dataset(s)

Nature of Aberration

Cytological Order

Progenitor

Mutagen

X ray

Class of aberration (relative to wild type)

chromosomal_deletion

(FlyBase, 2007)

Class of aberration (relative to progenitor)

chromosomal_deletion

(Broadie and Bate, 1993, Ganetzky, 1984)

Breakpoints

[];[]

(Ganetzky, 1984)

14C6-14D1;14C6-14D1

(Broadie and Bate, 1993)

Causes alleles

Carries alleles

Transposon Insertions

Formalized genetic data

bk1 << l(1)14DEb << l(1)14DEa << bk2 << r

Genetic mapping information

Comments

Comments on Cytology

A small deficiency in para.

(Broadie and Bate, 1993)

Cytologically invisible deletion.

(Ganetzky, 1984)

Left limit of break 1 from polytene analysis (FBrf0064379) Right limit of break 1 from inclusion of para (FBrf0040979) Left limit of break 2 from inclusion of para (FBrf0040979) Right limit of break 2 from polytene analysis (FBrf0064379)

Sequence Crossreferences

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

Gene Deletion and Duplication Data

Genes Deleted / Disrupted

Complementation Data

Completely deleted / disrupted

l(1)14DEa

(Ganetzky, 1984)

l(1)14DEb

(Ganetzky, 1984)

para

(Kueppers et al., 2003, Ganetzky, 1984)

Partially deleted / disrupted

Molecular Data

Completely deleted

Partially deleted

Genes NOT Deleted / Disrupted

Complementation Data

Molecular Data

Genes Duplicated

Complementation Data

Completely duplicated

Partially duplicated

Molecular Data

Completely duplicated

Partially duplicated

Genes NOT Duplicated

Complementation Data

Molecular Data

Affected Genes Inferred by Location (0)

If no genes are listed here, it may be because the affected region is very large. The JBrowse insert above may show an error for the same reason, and other FlyBase tools such as CytoSearch may also fail for large regions. You can contact FlyBase for more help.
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Related Comments

Phenotypic Data

In combination with other aberrations

NOT in combination with other aberrations

The transient and persistent components of the voltage-gated Na⁺ current are absent in Df(1)D34 aCC/RP2 neurons.

(Mee et al., 2004)

Shows normal GABA staining in stage 17 nerve cord.

(Kueppers et al., 2003)

Df(1)D34 embryos show a reduction in the frequency and amplitude of "EPSC-like" currents (inward currents that can reach 25pA in amplitude and have a rapid activation but slower inactivation in wild-type embryos) in CNS neurons.

(Baines and Bate, 1998)

Late embryonic lethal. para^ts1/Df(1)D34 die as first instar larvae. Greatly reduced synaptic activity, all bursting activity is absent, both frequency and amplitude of excitatory junction currents (EJCs) are greatly reduced at the embryonic neuromuscular junction (NMJ). In homozygotes postsynaptic expression of GluRIIA is significantly reduced by the end of embryogenesis.

(Broadie and Bate, 1993)

Lethal over para⁺ in an mle^nap-ts1 background.

(Ganetzky, 1984)

Stocks (0)

Notes on Origin

Discoverer

M.M. Green.

Balancer / Genotype Variants of the Aberration

Separable Components

Other Comments

Synonyms and Secondary IDs (10)

Reported As

Symbol Synonym

D³⁴

(Sanchez et al., 1994)

Df(1)D34

(Song and Tanouye, 2007, Mee et al., 2004)

Df(1)LD34

(Baines and Bate, 1998, Broadie and Bate, 1993)

Df(1)l-D34

Df(1)l^D34

(Chiang and Kurnit, 2003, Ganetzky, 1984)

Df(1)lD34

(Folkers et al., 1993)

Df^para

(Broadie and Bate, 1993)

para^Df(1)D34

(Lindsay et al., 2008)

para^ld34

(Fergestad et al., 2006)

Name Synonyms

paralyticDf(1)LD34

(Kueppers et al., 2003)

Secondary FlyBase IDs

References (14)

Report Sections

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