FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Aberration: Dmel\Dp(3;3)E(var)88D8
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General Information
Symbol
Dp(3;3)E(var)88D8
Species
D. melanogaster
Name
Duplication (3;3) Enhancer of variegation
FlyBase ID
FBab0003702
Feature type
tandem_duplication
Computed Breakpoints include

88D4-88D6;88E4-88F2

Features within 88D4--88F2
Sequence coordinates
Member of large scale dataset(s)
Nature of Aberration
Cytological Order
Progenitor
Mutagen
P-element activity
PM hybrid dysgenesis
(Locke et al., 1988)
Class of aberration (relative to wild type)
tandem_duplication
(FlyBase, 2007)
Class of aberration (relative to progenitor)
tandem_duplication
(Locke et al., 1988)
Breakpoints

88D4-88D6;88E4-88F2

(Locke et al., 1988)
Causes alleles
E(var)88DE8
(Locke, 1993, Locke et al., 1988)
Carries alleles
Transposon Insertions
Formalized genetic data

wrl << bk1 << E(var)88D << bk2

Genetic mapping information
Comments
Comments on Cytology

All limits from polytene analysis (FBrf0048198) Tandem duplication presumably revertable by unequal crossing over.

Sequence Crossreferences
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
Gene Deletion and Duplication Data
Genes Deleted / Disrupted
Complementation Data
Completely deleted / disrupted
E(var)88D
(Locke, 1993)
Partially deleted / disrupted
Molecular Data
Completely deleted
Partially deleted
Genes NOT Deleted / Disrupted
Complementation Data
 
Molecular Data
 
Genes Duplicated
Complementation Data
Completely duplicated
E(var)88D
(Tartof et al., 1989)
Partially duplicated
Molecular Data
Completely duplicated
Partially duplicated
Genes NOT Duplicated
Complementation Data
 
Molecular Data
 
Affected Genes Inferred by Location (0)
    If no genes are listed here, it may be because the affected region is very large. The JBrowse insert above may show an error for the same reason, and other FlyBase tools such as CytoSearch may also fail for large regions. You can contact FlyBase for more help.
    In these cases, there will be no "Export to Hitlist" button to the left.
    Phenotypic Data
    In combination with other aberrations

    Dp(3;3)E(var)88D8 has no effect on the frequency of X-Y chromosome nondisjunction seen in Df(1)X-1-53B males.

    (McKee et al., 2000)

    Effect on variegation of y in In(1)y3P and Sb in T(2;3)SbV studied: inactivation of y occurs independently of inactivation of Sb.

    (Bishop, 1992)

    Enhances position-effect variegation in In(1)wm4.

    NOT in combination with other aberrations

    Enhancer of variegation.

    (Tartof et al., 1989)

    Homozygous lethal.

    (Locke et al., 1988)
    Stocks (0)
    Notes on Origin
    Discoverer
     
    Balancer / Genotype Variants of the Aberration
     
    Separable Components
     
    Other Comments
     

    Spontaneous revertants of the dominant enhancer phenotype are accompanied by loss of the duplication.

    (Tartof et al., 1989)
    Synonyms and Secondary IDs (6)
    Reported As
    Symbol Synonym
    3-9E8
    (McKee et al., 2000)
    Dp(3;3)E(var)88D#8
    (Bishop, 1992)
    Dp(3;3)E(var)88D8
    Dp(3;3)E8
    (Locke et al., 1988)
    E8
    (Tartof et al., 1989)
    Name Synonyms
    Duplication (3;3) Enhancer of variegation
    Secondary FlyBase IDs
      References (8)