FB2026_02 , released June 18, 2026
Aberration: Dmel\In(1)l-v231
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General Information
Symbol
In(1)l-v231
Species
D. melanogaster
Name
Inversion (1) lethal variegated
FlyBase ID
FBab0004144
Feature type
chromosomal_inversion
Computed Breakpoints include

1C-1D;20F

Sequence coordinates
Member of large scale dataset(s)
Nature of Aberration
Cytological Order
Progenitor
Mutagen
X ray
(Lindsley et al., 1960)
Class of aberration (relative to wild type)
chromosomal_inversion
(FlyBase, 2007)
Class of aberration (relative to progenitor)
chromosomal_inversion
(Lindsley et al., 1960)
Breakpoints

1C-1D;19-20

(Lindsley et al., 1960)
Causes alleles
Carries alleles
Transposon Insertions
Formalized genetic data

bk1 << l(1)v231 << bk2

Genetic mapping information
Comments
Comments on Cytology

Limits of break 1 from polytene analysis (FBrf0013319) Limits of break 2 from polytene analysis (citation unavailable)

Sequence Crossreferences
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
Gene Deletion and Duplication Data
Genes Deleted / Disrupted
Complementation Data
Completely deleted / disrupted
Partially deleted / disrupted
Molecular Data
Completely deleted
Partially deleted
Genes NOT Deleted / Disrupted
Complementation Data
 
Molecular Data
 
Genes Duplicated
Complementation Data
Completely duplicated
Partially duplicated
Molecular Data
Completely duplicated
Partially duplicated
Genes NOT Duplicated
Complementation Data
 
Molecular Data
 
Affected Genes Inferred by Location (0)
    If no genes are listed here, it may be because the affected region is very large. The JBrowse insert above may show an error for the same reason, and other FlyBase tools such as CytoSearch may also fail for large regions. You can contact FlyBase for more help.
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    Phenotypic Data
    In combination with other aberrations

    In(1)l-v231 males carrying the free duplication Dp(2;f)e51 show 26% viability relative to controls.

    (Berloco et al., 2014)

    In(1)l-v231 males carrying the free duplication Dp(2;f)e58 show 53% viability relative to controls.

    (Berloco et al., 2014)

    In(1)l-v231 males carrying the free duplication Dp(2;f)e97 show 58% viability relative to controls.

    (Berloco et al., 2014)

    Autosomal heterochromatin also appears to suppress the lethality of In(1)l-v231 in a dosage-dependent manner.

    (Berloco et al., 2014)

    Males carrying In(1)l-v231 and Dp(1;f)1173 show 47% viability relative to controls.

    (Berloco et al., 2014)

    Males carrying In(1)l-v231 and Dp(1;f)1205 show 13% viability relative to controls.

    (Berloco et al., 2014)

    Males carrying In(1)l-v231 and Dp(1;f)1346 show 14% viability relative to controls.

    (Berloco et al., 2014)

    The viability of In(1)l-v231 males depends on the amount of X heterochromatin. Males carrying In(1)l-v231 and the free duplication Dp(1;f)1187 are only 6% as viable as controls. The viability increases with the amount of X heterochromatin. Males carrying In(1)l-v231 and Dp(1)A140 show 66% viability relative to controls.

    (Berloco et al., 2014)
    NOT in combination with other aberrations

    In(1)l-v231 show variegating lethality.

    (Berloco et al., 2014)

    X/0 males are lethal (relative viability of 0.01), X/Y males are viable (relative viability of 0.96). Levels of maternal nondisjunction are low. Males are fertile. Recovery of male lethals cannot be reduced when in combination with either E(var)71 or Df(2R)M41A10.

    (Lindsley et al., 1960)

    Surviving X0 males have rough reduced eyes. XY male fully viable viability X0: <.01 XY male fertile

    Stocks (0)
    Notes on Origin
    Discoverer
     

    Selected as X chromosomes lethal or semilethal in X0 males, but viable in XY males.

    Balancer / Genotype Variants of the Aberration
     
    Separable Components
     
    Other Comments
     
    Synonyms and Secondary IDs (5)
    Reported As
    Symbol Synonym
    In(1)l v231
    (Berloco et al., 2014)
    In(1)l-v231
    In(1)lv231
    (Liu and Wolfner, 1998)
    l(1)v231
    Name Synonyms
    Inversion (1) lethal variegated
    Secondary FlyBase IDs
    • FBal0007908
    References (6)