FB2026_03 , released September 17, 2026
Aberration: Dmel\In(2LR)SM6
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General Information
Symbol
In(2LR)SM6
Species
D. melanogaster
Name
FlyBase ID
FBab0004818
Feature type
chromosomal_inversion
Computed Cytological Breakpoints (relative to progenitor)
Sequenced Breakpoints (relative to progenitor)
Member of large scale dataset(s)
Nature of Aberration
Cytological Order

2Lt - 22A3 | 60B - 58B1 | 42A3 - 50C10 | 30E - 22D | 34A1 - 42A2 | 58A4 - 50D1 | 30F - 33F5 | 22D1 - 22B1 | 60C - 2Rt

Progenitor
In(2LR)CyO
(Craymer, 1984)
In(2LR)SM1
(Craymer, 1984)
Mutagen
recombination
Class of aberration (relative to wild type)
chromosomal_inversion
Class of aberration (relative to progenitor)
Cytological Breakpoints (relative to progenitor)
Causes alleles
Carries alleles
Transposon Insertions
Formalized genetic data
Genetic mapping information
Comments
Comments on Cytology
Sequence Crossreferences
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
Gene Deletion and Duplication Data
Genes Deleted / Disrupted
Complementation Data
Completely deleted / disrupted
Partially deleted / disrupted
Molecular Data
Completely deleted
Partially deleted
Genes NOT Deleted / Disrupted
Complementation Data
 
Molecular Data
 
Genes Duplicated
Complementation Data
Completely duplicated
Partially duplicated
Molecular Data
Completely duplicated
Partially duplicated
Genes NOT Duplicated
Complementation Data
 
Molecular Data
 
Affected Genes Inferred by Location (0)
    If no genes are listed here, it may be because the affected region is very large. The JBrowse insert above may show an error for the same reason, and other FlyBase tools such as CytoSearch may also fail for large regions. You can contact FlyBase for more help.
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    Phenotypic Data
    In combination with other aberrations
    NOT in combination with other aberrations
    Stocks (0)
    Notes on Origin
    Discoverer

    Craymer, 1979.

    (Craymer, 1984)

    Craymer.

     

    "SM6" is an umbrella term for SM6a and SM6b, which were generated independently but in identical ways. Both were made by recombination between CyO (a 2LR inversion of 30E-F;50C10-D1 superimposed on In(2L)Cy (22D1-2;33F5-34A1) and In(2R)Cy (42A2-3;58A4) and SM1 (a 2LR inversion of 22A3-B1;60B-C superimposed on In(2L)Cy and In(2R)Cy).

    (Parks and Cook, 2026.8.6)
    Balancer / Genotype Variants of the Aberration
    Separable Components
     
    Other Comments
     

    SM6a and SM6b variants carry slightly different marker sets. The following is a list of known SM6 variants and their markers. SM6a : al[2] Duox[Cy] dpy[lvI] cn[2P] speck[2]. SM6b: al[2] Duox[Cy] amos[Roi-1] dpy[lvI] cn[2P] speck[2]. SM6#16 : Ab(2)SM6#16, al[2] Duox[Cy] dpy[lvI] cn[2P] speck[2] - this is an X-ray derivative of SM6a, presumably has additional aberrations.

    (Parks and Cook, 2026.8.6)

    Suppresses recombination over entire chromosome 2.

    Synonyms and Secondary IDs (3)
    Reported As
    Symbol Synonym
    In(2LR)SM6
    SM6
    (Parks and Cook, 2026.8.6, Craymer, 1984)
    Name Synonyms
    Second Multiple Six
    (Craymer, 1984)
    Secondary FlyBase IDs
      References (24)