FB2026_03 , released September 17, 2026
Aberration: Dmel\Df(2L)k07716-V.1
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General Information
Symbol
Df(2L)k07716-V.1
Species
D. melanogaster
Name
FlyBase ID
FBab0038762
Feature type
chromosomal_deletion
Computed Cytological Breakpoints (relative to progenitor)
Features within 32E2--32E2
Sequenced Breakpoints (relative to progenitor)
Member of large scale dataset(s)
Nature of Aberration
Cytological Order
Progenitor
P{lacW}canak07716
(Ciapponi et al., 2004)
Mutagen
P-element activity
(Ciapponi et al., 2004)
Class of aberration (relative to wild type)
chromosomal_deletion
(FlyBase, 2007)
Class of aberration (relative to progenitor)
chromosomal_deletion
(Ciapponi et al., 2004)
Cytological Breakpoints (relative to progenitor)

[];[]

(Ciapponi et al., 2004)
Causes alleles
canak07716-V.1
(Ciapponi et al., 2004)
Carries alleles
Transposon Insertions
Formalized genetic data
Genetic mapping information
Comments
Comments on Cytology
Sequence Crossreferences
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
Gene Deletion and Duplication Data
Genes Deleted / Disrupted
Complementation Data
Completely deleted / disrupted
Partially deleted / disrupted
Molecular Data
Completely deleted
mre11
(Ciapponi et al., 2004)
Osi21
(Ciapponi et al., 2004)
Ppt2
(Ciapponi et al., 2004)
salr
(Ciapponi et al., 2004)
Partially deleted
cana
(Ciapponi et al., 2004)
Genes NOT Deleted / Disrupted
Complementation Data
 
Molecular Data
 
Genes Duplicated
Complementation Data
Completely duplicated
Partially duplicated
Molecular Data
Completely duplicated
Partially duplicated
Genes NOT Duplicated
Complementation Data
 
Molecular Data
 
Affected Genes Inferred by Location (0)
    If no genes are listed here, it may be because the affected region is very large. The JBrowse insert above may show an error for the same reason, and other FlyBase tools such as CytoSearch may also fail for large regions. You can contact FlyBase for more help.
    In these cases, there will be no "Export to Hitlist" button to the left.
    Phenotypic Data
    In combination with other aberrations

    Lethal in combination with Df(2L)FCK-20. Df(2L)FCK-20/Df(2L)k07716-V.1 animals die at the pupal stage and no adult escapers are seen. The mutant pharate adults have rough eyes, scalloped wings and bristles are shorter than normal or missing. Wings discs of mutant third instar larvae show high levels of apoptosis compared to control discs. Mitotic neuroblasts from Df(2L)FCK-20/Df(2L)k07716-V.1 larval brains show a high frequency of telomere fusions and chromosome breaks. Single telomeric associations (in which a single telomere fuses with either its sister telomere or a single non-sister telomere) and double telomere associations are seen. Metaphases with rearranged chromosomes and hyperploid/polyploid cells are seen. Chromosome breaks involving either one or both sister chromatids are seen. Df(2L)FCK-20/Df(2L)k07716-V.1 mutant cells are at least one order of magnitude more sensitive than wild-type cells to the induction of chromosome breaks by irradiation.

    (Ciapponi et al., 2004)
    NOT in combination with other aberrations
    Stocks (0)
    Notes on Origin
    Discoverer
     
    Balancer / Genotype Variants of the Aberration
     
    Separable Components
     
    Other Comments
     

    FlyBase curator comment: The combination Df(2L)FCK-20/Df(2L)k07716-V.1 is referred to as "mre11DC".

    (Ciapponi et al., 2006)
    Synonyms and Secondary IDs (2)
    Reported As
    Symbol Synonym
    Df(2L)K07716-V.1
    (Ciapponi et al., 2004)
    Df(2L)k07716-V.1
    Name Synonyms
    Secondary FlyBase IDs
      References (3)