FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Aberration: Dmel\Df(2L)VGlut12
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General Information
Symbol
Df(2L)VGlut12
Species
D. melanogaster
Name
FlyBase ID
FBab0047084
Feature type
Also Known As
Df(2L)VGlut2
Computed Breakpoints include
Sequence coordinates
Member of large scale dataset(s)
Nature of Aberration
Cytological Order
Progenitor
VGlut1KG06301
(Daniels et al., 2006)
Mutagen
Delta2-3 transposase
(Daniels et al., 2006)
Class of aberration (relative to wild type)
Class of aberration (relative to progenitor)
Breakpoints
Causes alleles
Carries alleles
Transposon Insertions
Formalized genetic data
Genetic mapping information
Comments
Comments on Cytology
Sequence Crossreferences
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
Gene Deletion and Duplication Data
Genes Deleted / Disrupted
Complementation Data
Completely deleted / disrupted
Partially deleted / disrupted
Molecular Data
Completely deleted
Partially deleted
CG18641
(Daniels et al., 2006)
VGlut1
(Daniels et al., 2006)
Genes NOT Deleted / Disrupted
Complementation Data
 
Molecular Data
 
Genes Duplicated
Complementation Data
Completely duplicated
Partially duplicated
Molecular Data
Completely duplicated
Partially duplicated
Genes NOT Duplicated
Complementation Data
 
Molecular Data
 
Affected Genes Inferred by Location (0)
    If no genes are listed here, it may be because the affected region is very large. The JBrowse insert above may show an error for the same reason, and other FlyBase tools such as CytoSearch may also fail for large regions. You can contact FlyBase for more help.
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    Phenotypic Data
    In combination with other aberrations
    NOT in combination with other aberrations

    In late pharate adults, Df(2L)VGlut12/Df(2L)VGlut12 somatic clones of persistent motor neurons which innervate the abdominal lateral tergosternal muscles have a slightly (but significantly) increased total axonal arbor length, with no difference in area of arbor coverage compared to wild-type controls.

    (Constance et al., 2018)

    Df(2L)VGlut12 is embryonic lethal.

    No synaptic events are detected in Df(2L)VGlut12 homozygous embryos, while spontaneous miniature excitatory unction curents (mEJCs) are abundant in wild-type. This defect is presynaptic as the response to pressure-ejected glutamate is not significantly different between wild-type and mutant muscles.

    (Daniels et al., 2006)
    Stocks (1)
    Notes on Origin
    Discoverer
     
    Balancer / Genotype Variants of the Aberration
     
    Separable Components
     
    Other Comments
     

    Df(2L)VGlut2 completely removes the VGlut coding region and disrupts the adjacent gene CG18641.

    (Daniels et al., 2006)
    Synonyms and Secondary IDs (6)
    Reported As
    Symbol Synonym
    Df(2L)VGlut12
    Df(2L)VGlut2
    (Fisher et al., 2017)
    Df(2L)dvglut2
    (Daniels et al., 2006)
    Df(2L)vglut2
    (Constance et al., 2018)
    VGlut2
    (Jeong et al., 2021)
    dvglut2
    (Rossano et al., 2017)
    Name Synonyms
    Secondary FlyBase IDs
      References (7)