FlyBase Aberration Report: Dmel\Df(1)sov

General Information

Symbol

Df(1)sov

Species

D. melanogaster

Name

FlyBase ID

FBab0049129

Feature type

chromosomal_deletion

Computed Breakpoints include

Features within 6C12--6C13 (Estimated cytology)

Genomic Maps

JBrowse

Sequence coordinates

X:6,756,569..6,756,569 (Df(1)sov:bk1)

(Benner et al., 2019)

X:6,770,708..6,770,708 (Df(1)sov:bk2)

(Benner et al., 2019)

Member of large scale dataset(s)

Nature of Aberration

Cytological Order

Progenitor

PBac{RB}e03842

(Benner et al., 2019)

P{XP}sov^d07849

(Benner et al., 2019)

Mutagen

FLPase

(Benner et al., 2019)

Class of aberration (relative to wild type)

chromosomal_deletion

(Benner et al., 2019)

Class of aberration (relative to progenitor)

chromosomal_deletion

(Benner et al., 2019)

Breakpoints

Causes alleles

Carries alleles

Transposon Insertions

P+PBac{XP5.RB3}X-194

(Benner et al., 2019)

Formalized genetic data

Genetic mapping information

Comments

FLP-mediated recombination between the PBac{RB}e03842 and P{XP}sov^d07849 insertions has resulted in the deletion of the genomic sequence between them, deleting the sov and lncRNA:CR43496 genes.

(Benner et al., 2019)

Comments on Cytology

Sequence Crossreferences

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

Gene Deletion and Duplication Data

Genes Deleted / Disrupted

Complementation Data

Completely deleted / disrupted

sov

(Hammond et al., 2020, Benner et al., 2019)

Partially deleted / disrupted

Molecular Data

Completely deleted

lncRNA:CR43496

(Benner et al., 2019)

sov

(Benner et al., 2019)

Partially deleted

Genes NOT Deleted / Disrupted

Complementation Data

Molecular Data

Genes Duplicated

Complementation Data

Completely duplicated

Partially duplicated

Molecular Data

Completely duplicated

Partially duplicated

Genes NOT Duplicated

Complementation Data

Molecular Data

Affected Genes Inferred by Location (2)

Related Comments

Phenotypic Data

In combination with other aberrations

Df(1)sov female germline clones do not produce vitellogenic egg chambers or mature eggs, a phenotype that is rescued by Dp(1;3)DC486.

(Benner et al., 2019)

The lethality of Df(1)sov is rescued by Dp(1;3)sn^13a1 and Dp(1;3)DC486.

(Benner et al., 2019)

NOT in combination with other aberrations

Df(1)sov is recessive lethal, as individuals do not reach adulthood; heterozygotes are viable and fertile. The lethality is rescued by sov^FSTF-sfGFP.

Df(1)sov is a dominant suppressor of position-effect variegation by P{hsp26-pt-T}118E-10, P{hsp26-pt-T}Dyrk3^118E-15, P{hsp26-pt-T}118E-3, P{hsp26-pt-T}39C-2 or P{hsp26-pt-T}39C-12.

Df(1)sov female germline clones do not produce vitellogenic egg chambers or mature eggs.

(Benner et al., 2019)

Stocks (1)

Bloomington

91361

Df(1)sov, w¹¹¹⁸ P{neoFRT}19A; Dp(1;3)DC486, PBac{DC486}VK00033

Notes on Origin

Discoverer

Balancer / Genotype Variants of the Aberration

Separable Components

Other Comments