FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Aberration: Dmel\Df(3L)CRIMIC-CR71051
Open Close
General Information
Symbol
Df(3L)CRIMIC-CR71051
Species
D. melanogaster
Name
FlyBase ID
FBab0049404
Feature type
Computed Breakpoints include
Sequence coordinates
3L:7,538,903..7,538,903 (Df(3L)CRIMIC-CR71051:bk1)
3L:7,539,837..7,539,837 (Df(3L)CRIMIC-CR71051:bk2)
Member of large scale dataset(s)
Nature of Aberration
Cytological Order
Progenitor
Class of aberration (relative to wild type)
Class of aberration (relative to progenitor)
Breakpoints
Carries alleles
Formalized genetic data
Genetic mapping information
Comments

A TI{KozakGAL4} DNA cassette has been inserted into CG16998, replacing the coding sequence (coordinates of deleted sequence are 3L:7538903..7539837 , release 6 genome). The 3' end of the deletion extends 156 bp downstream of the annotated 3' end of the CG16998 gene. This results in a simultaneous knock-out of CG16998 plus a knock-in of GAL4 that is expected to be expressed under the control of the endogenous regulatory sequences of CG16998 (predicted to gene trap all annotated transcripts of the gene). The deletion also removes part of the 3' UTR of the lqf-RH isoform (none of the transcribed regions of the other annotated lqf isoforms are deleted). The TI{KozakGAL4} cassette was inserted via the CRISPR/Cas-9 drop-in technique, using a dsDNA donor vector with a 3' homology arm of length 200bp and the 5' homology arm extended to restore the promoter. The sgRNA sequences used to target the gene were: AGTAGGTCGCATGCCAAACCCGG and AGAGCGGCTCCTCAGATGGCTGG.

Comments on Cytology
Sequence Crossreferences
DNA sequence
Protein sequence
Gene Deletion and Duplication Data
Genes Deleted / Disrupted
Complementation Data
Completely deleted / disrupted
Partially deleted / disrupted
Molecular Data
Completely deleted
Genes NOT Deleted / Disrupted
Complementation Data
 
Molecular Data
 
Genes Duplicated
Complementation Data
Completely duplicated
Partially duplicated
Molecular Data
Completely duplicated
Partially duplicated
Genes NOT Duplicated
Complementation Data
 
Molecular Data
 
Affected Genes Inferred by Location (2)
Phenotypic Data
In combination with other aberrations
NOT in combination with other aberrations
Stocks (1)
Notes on Origin
Discoverer
 
Balancer / Genotype Variants of the Aberration
 
Separable Components
 
Other Comments
 
Synonyms and Secondary IDs (1)
Reported As
Symbol Synonym
Df(3L)CRIMIC-CR71051
Name Synonyms
Secondary FlyBase IDs
    References (1)