FB2026_02 , released June 18, 2026
Allele: Dmel\Adhfn46
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General Information
Symbol
Dmel\Adhfn46
Species
D. melanogaster
Name
FlyBase ID
FBal0000331
Feature type
allele
Associated gene
Dmel\Adh
Associated Insertion(s)
Carried in Construct
Key Links
Allele class

loss of function allele

Mutagen
Nature of the Allele
Allele class

loss of function allele

(Le et al., 1990)
Mutagen
formaldehyde
(Le et al., 1990)
Progenitor genotype
AdhF
(Le et al., 1990)
Cytology
Description

The pattern of deletion and deletion accompanied by sequence addition of 3-11 bp direct repeat sequences at the mutant sites suggests a slipped mispairing.

(Le et al., 1990)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
X78917
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference

      Adh CRM is presentat 3% of that in the parental strain in Adhfn46 adults.

      (Le et al., 1990)
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer

      Sofer.

      Comments
      Comments

      Adults and larvae accumulate abundant truncated Adh transcripts. The shorter Adh protein is present at 3% wild type levels.

      (Le et al., 1990)
      External Crossreferences and Linkouts ( 1 )
      Crossreferences
      GenBank Nucleotide - A collection of sequences from several sources, including GenBank, RefSeq, TPA, and PDB.
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      Adhfn46
      Name Synonyms
      Secondary FlyBase IDs
        References (1)