FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\AdhnLA248
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General Information
Symbol
Dmel\AdhnLA248
Species
D. melanogaster
Name
FlyBase ID
FBal0000355
Feature type
allele
Associated gene
Dmel\Adh
Associated Insertion(s)
Carried in Construct
Key Links
Allele class

loss of function allele

amorphic allele - genetic evidence

Mutagen
Nature of the Allele
Allele class

amorphic allele - genetic evidence

(Moses et al., 1990)

loss of function allele

(White and Jacobson, 1996)
Mutagen
X ray
(Brogna and Ashburner, 1997, Fossett et al., 1994, Mahmoud et al., 1991, Savakis et al., 1986)
Progenitor genotype
AdhF
Cytology

Polytene chromosomes normal.

(Ashburner et al., 1982)
Description

Tandem duplication within the Adh gene.

(Brogna and Ashburner, 1997)

Complex duplication (cytology not discussed).

(Mahmoud et al., 1991)

250 bp insertion formed by unequal crossover between exon 3 (at +708) and exon 2 (at +465) with 7bp (GTGCAAC) inserted at the junction.

Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
M17845
AAA28363
 
UniProtKB/Swiss-Prot
UniProtKB/TrEMBL
    Expression Data
    Reporter Expression
    Additional Information
    Statement
    Reference
     
    Marker for
    Reflects expression of
    Reporter construct used in assay
    Human Disease Associations
    Disease Ontology (DO) Annotations
    Models Based on Experimental Evidence ( 0 )
    Disease
    Evidence
    References
    Modifiers Based on Experimental Evidence ( 0 )
    Disease
    Interaction
    References
    Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
     
    Disease-implicated variant(s)
     
    Phenotypic Data
    Phenotypic Class
    Phenotype Manifest In
    Detailed Description
    Statement
    Reference
    External Data
    Interactions
    Show genetic interaction network for Enhancers & Suppressors
    Phenotypic Class
    Phenotype Manifest In
    Additional Comments
    Genetic Interactions
    Statement
    Reference
    Xenogenetic Interactions
    Statement
    Reference
    Complementation and Rescue Data
    Comments
    Images (0)
    Mutant
    Wild-type
    Stocks (0)
    Notes on Origin
    Discoverer

    Aaron.

    Selected as: Pentenol resistant adult.

    Comments
    Comments

    CRM negative.

    Used, carried in P-element vectors along with other Adh alleles, to study gene conversion and unequal crossing over to re-generate "Adh+".

    (Hipeau-Jacquotte et al., 1989)
    External Crossreferences and Linkouts ( 3 )
    Crossreferences
    GenBank Nucleotide - A collection of sequences from several sources, including GenBank, RefSeq, TPA, and PDB.
    GenBank Protein - A collection of sequences from several sources, including translations from annotated coding regions in GenBank, RefSeq and TPA, as well as records from SwissProt, PIR, PRF, and PDB.
    UniProt/Swiss-Prot - Manually annotated and reviewed records of protein sequence and functional information
    Synonyms and Secondary IDs (1)
    Reported As
    Symbol Synonym
    AdhnLA248
    (Wu et al., 1998)
    Name Synonyms
    Secondary FlyBase IDs
      References (15)