FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\btD
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General Information
Symbol
Dmel\btD
Species
D. melanogaster
Name
Dominant
FlyBase ID
FBal0001328
Feature type
allele
Associated gene
Dmel\bt
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
X ray
Progenitor genotype
Cytology
Description

Breakpoint within or just N-terminal to the kinase domain.

(Ayme-Southgate et al., 1995)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Homozygotes die as late embryos. btD/btl-a transheterozygotes die as embryos.

      (Ayme-Southgate et al., 1995)

      Embryo cannot hatch from vitelline membrane: due to muscle weakness: embryo is flaccid. Heterozygous adults have a slight bristle phenotype.

      (Fyrberg et al., 1992)

      When found showed regularly divergent wings with some angular bend near base. Legs lumpy at low temperature. Preleg bristles present as in bt1.

      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Fails to complement

      btl-k

      (Ayme-Southgate et al., 1995)

      btl-f

      (Ayme-Southgate et al., 1995)

      btl-b

      (Ayme-Southgate et al., 1995)

      btl-a

      (Ayme-Southgate et al., 1995)
      Comments

      Fails to complement alleles of the l(4)23 complementation group.

      (Ayme-Southgate et al., 1995)
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer

      Schultz, 11th Jan. 1933.

      Comments
      Comments

      bt phenotype no longer observed (Hochman, 1976).

      Balanced stocks in existence today show only preleg bristle character and recessive lethality.

      (Lindsley and Zimm, 1992)

      Molecular analysis of the "Df(4)bt-D" rearrangement indicates that it is not a deficiency or a translocation. The most probable rearrangement is an inversion, or possibly a relatively large insertion. The banding pattern of the polytene chromosomes is normal.

      (Ayme-Southgate et al., 1995)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (8)
      Reported As
      Symbol Synonym
      Df(4)2c
      Df(4)bt-D
      btD
      lf(4)2-btD
      (Hochman, 1976, Hochman, 1974)
      lf(4)2bt-D
      (Hochman, 1971)
      Name Synonyms
      Deficiency(4)bent-Dominant
      Dominant
      lethal factor(4)bt-D
      (Hochman, 1971)
      Secondary FlyBase IDs
      • FBab0002962
      References (11)