FB2026_02 , released June 18, 2026
Allele: Dmel\csw7
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General Information
Symbol
Dmel\csw7
Species
D. melanogaster
Name
FlyBase ID
FBal0001926
Feature type
allele
Associated gene
Dmel\csw
Associated Insertion(s)
Carried in Construct
Also Known As
csw19-106
Key Links
Allele class

hypomorphic allele - genetic evidence

Mutagen
Nature of the Allele
Allele class

hypomorphic allele - genetic evidence

(Perkins et al., 1992)
Mutagen
spontaneous
(Perkins et al., 1996, Perkins et al., 1992, Schalet, 1986, Kramers et al., 1983)
Progenitor genotype
Cytology
Description
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      csw7 germline clone mosaics cause maternal effect lethality. Embryos derived from mothers with germline clones that exhibit a corkscrew cuticle phenotype (8%) have slight paternal rescue of the germline clone phenotype, embryos that do not receive a wild type copy from their father (92%), null embryos, die with a 'U'-shaped cuticle phenotype.

      (Perkins et al., 1996)

      Abnormal development of terminal internal structures.

      (Perkins et al., 1992)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer

      Schalet.

      (Kramers et al., 1983)
      Comments
      Comments

      Phenotypic series of csw mutant embryos derived from homozygous germline clones, classified according to cuticular phenotype: csw5 = cswLE120 > csw1 = csw13-87 > cswe13d.3 > csw7 = csw6.

      (Perkins et al., 1996)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (4)
      Reported As
      Symbol Synonym
      19-106
      (Kramers et al., 1983)
      csw19-106
      (Ghiglione et al., 1999, Perkins et al., 1996, Perkins et al., 1992)
      csw7
      l(1)19-106
      (Schalet, 1986)
      Name Synonyms
      Secondary FlyBase IDs
        References (5)