FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\cup3
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General Information
Symbol
Dmel\cup3
Species
D. melanogaster
Name
FlyBase ID
FBal0002148
Feature type
allele
Associated gene
Dmel\cup
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
ethyl methanesulfonate
(Keyes and Spradling, 1997, Schupbach and Wieschaus, 1991)
Progenitor genotype
Cytology
Description
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Egg chambers arrest at stage S5-6. Nurse cell nuclear chromatin in the oldest egg chambers has the appearance of normal S5 chromatin.

      (Keyes and Spradling, 1997)

      Eggs have fused dorsal appendages.

      (Schupbach and Wieschaus, 1991)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Suppressor of
      Statement
      Reference

      cup3 is a suppressor of phenotype of nanos18

      (Verrotti and Wharton, 2000)
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescued by

      cup01355/cup3 is rescued by Scer\GAL4VP16.nanos.UTR/cupUAS.cNa

      (Nelson et al., 2004)
      Partially rescued by

      cup01355/cup3 is partially rescued by Scer\GAL4VP16.nanos.UTR/cupMT.UAS.cNa

      (Nelson et al., 2004)
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      cup3
      cupPB53
      Name Synonyms
      Secondary FlyBase IDs
        References (4)