FlyBase Allele Report: Dmel\dl[24]

General Information

Symbol

Dmel\dl²⁴

Species

D. melanogaster

Name

FlyBase ID

FBal0002666

Feature type

allele

Associated gene

Dmel\dl

Associated Insertion(s)

Carried in Construct

Also Known As

dl^D4

Key Links

Allele class

antimorphic allele - genetic evidence

Mutagen

ethyl methanesulfonate

Nature of the Allele

Allele class

antimorphic allele - genetic evidence

(Govind et al., 1992)

Mutagen

ethyl methanesulfonate

(Szabad et al., 1989)

Progenitor genotype

Cytology

Description

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

female sterile germline-dependent | dominant

(Szabad et al., 1989)

female sterile soma-dependent | dominant

(Szabad et al., 1989)

lethal | dominant | maternal effect

(Govind et al., 1992)

Phenotype Manifest In

cephalopharyngeal skeleton | embryonic stage

(Szabad et al., 1989)

Detailed Description

Statement

Reference

Strongly dorsalized phenotype in embryos when mothers are heterozygous for dl²⁴ and a deficiency for dl. Weakly dorsalized phenotype in embryos when mothers are heterozygous for dl²⁴ and wild type. Phenotypes can be rescued to weakly dorsalized with 75% hatching by an additional copy of dl⁺ carried in P{dl^hs.P}.

(Govind et al., 1992)

Embryos derived from heterozygous females have a range of phenotypes, from a disarranged head skeleton to a "tail-up" phenotype.

(Szabad et al., 1989)

dominant

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Rescued by

dl²⁴ is rescued by dl^Hsp83.PG

(Govind et al., 1992)

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

Comments

Analysis of germ-line chimeras shows that this mutation is both germ-line and soma-dependent.

(Szabad et al., 1989)

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

dl²⁴

dl^D4

(Govind et al., 1992, Szabad et al., 1989)

Name Synonyms

Secondary FlyBase IDs

References (2)

Report Sections

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