FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\E(spl)m8-HLHrv29
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General Information
Symbol
Dmel\E(spl)m8-HLHrv29
Species
D. melanogaster
Name
FlyBase ID
FBal0003350
Feature type
allele
Associated gene
Dmel\E(spl)m8-HLH
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
X ray
(Ziemer et al., 1988)
Progenitor genotype
E(spl)m8-HLH1
(Ziemer et al., 1988)
Cytology

Polytene chromosomes normal.

(Ziemer et al., 1988)
Description

lesion in -15.5 to -11.5 kb

Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Lethal in combination with E(spl)1. Homozygotes have variable neural hyperplasia.

      (Ziemer et al., 1988)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Other
      Statement
      Reference

      E(spl)m8-HLHrv29, gro1 has lethal phenotype

      (Ziemer et al., 1988)
      Phenotype Manifest In
      Enhancer of
      Statement
      Reference

      E(spl)m8-HLHrv29 is an enhancer of phenotype of Nspl-1

      (Ziemer et al., 1988)
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Homozygotes have weak enhancement of the Nspl-1 phenotype.

      (Ziemer et al., 1988)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Fails to complement

      E(spl)m8-HLH1

      (Ziemer et al., 1988)
      Comments

      Failure to complement assessment based on lethal phenotype.

      (Ziemer et al., 1988)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      E(spl)R-F4.4
      (Ziemer et al., 1988)
      E(spl)rv29
      E(spl)m8-HLHrv29
      Name Synonyms
      Secondary FlyBase IDs
        References (2)