FB2026_02 , released June 18, 2026
Allele: Dmel\E(tuh-1)1
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General Information
Symbol
Dmel\E(tuh-1)1
Species
D. melanogaster
Name
FlyBase ID
FBal0003355
Feature type
allele
Associated gene
E(tuh-1)
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Mutagen
    Nature of the Allele
    Allele class
    Mutagen
    Progenitor genotype
    Cytology
    Description
    Mutations Mapped to the Genome
    Curation Data
    Type
    Location
    Additional Notes
    References
    Variant Molecular Consequences
    Associated Sequence Data
    DDBJ / EMBL / GenBank
    DNA sequence
    Protein sequence
     
    UniProtKB/Swiss-Prot
      UniProtKB/TrEMBL
        Expression Data
        Reporter Expression
        Additional Information
        Statement
        Reference
         
        Marker for
        Reflects expression of
        Reporter construct used in assay
        Human Disease Associations
        Disease Ontology (DO) Annotations
        Models Based on Experimental Evidence ( 0 )
        Disease
        Evidence
        References
        Modifiers Based on Experimental Evidence ( 0 )
        Disease
        Interaction
        References
        Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
         
        Disease-implicated variant(s)
         
        Phenotypic Data
        Phenotypic Class
        Phenotype Manifest In
        Detailed Description
        Statement
        Reference

        Increases penetrance by 8% and expressivity by 91% for the tumorous-head trait.

        External Data
        Interactions
        Show genetic interaction network for Enhancers & Suppressors
        Phenotypic Class
        Phenotype Manifest In
        Enhancer of
        Statement
        Reference

        E(tuh-1)1 is an enhancer of phenotype of tuh1unspecified

        (Kuhn and Packert, 1988)

        E(tuh-1)1 is an enhancer of phenotype of tuh1h

        (Nickla and Carney, 1984)
        Additional Comments
        Genetic Interactions
        Statement
        Reference

        Acts in trans to Abd-Biab9-tuh-3 to increase maternal effect of tuh1 on transformation of head to abdominal structures.

        (Kuhn and Packert, 1988)

        Dramatically increases the frequency of head defects in animals derived from tuh1h females, and shifts the distribution of thoracic defects in the tumorous-head (CT) strain (whose phenotype may depend on tuh1 and Abd-Biab9-tuh-3) anteriorly.

        (Nickla and Carney, 1984)
        Xenogenetic Interactions
        Statement
        Reference
        Complementation and Rescue Data
        Comments
        Images (0)
        Mutant
        Wild-type
        Stocks (0)
        Notes on Origin
        Discoverer
        External Crossreferences and Linkouts ( 0 )
        Synonyms and Secondary IDs (1)
        Reported As
        Symbol Synonym
        E(tuh-1)1
        Name Synonyms
        Secondary FlyBase IDs
          References (2)