FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\E(z)65
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General Information
Symbol
Dmel\E(z)65
Species
D. melanogaster
Name
FlyBase ID
FBal0003444
Feature type
allele
Associated gene
Dmel\E(z)
Associated Insertion(s)
Carried in Construct
Key Links
Allele class

loss of function allele

amorphic allele - genetic evidence

Mutagen
Nature of the Allele
Allele class

amorphic allele - genetic evidence

(Jones and Gelbart, 1993)

loss of function allele

Mutagen
gamma ray
(Jones and Gelbart, 1993, Jones and Gelbart, 1990)
Progenitor genotype
E(z)1
(Jones and Gelbart, 1993, Jones and Gelbart, 1990)
Caused by aberration
T(2;3)E(z)65
Cytology
Description

4-5kb deletion flanking the third chromosome translocation breakpoint.

(Jones and Gelbart, 1993)

4-5kb deletion breaking in hay and E(z) transcription units.

(Mounkes et al., 1992)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Dominant suppressor of z mutants.

      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Suppressor of
      Statement
      Reference

      E(z)65 is a suppressor of phenotype of z1

      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer

      Revertant.

      (Jones and Gelbart, 1990)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (4)
      Reported As
      Symbol Synonym
      E(z)1R1
      (Mounkes et al., 1992)
      E(z)1R1
      E(z)65
      E(z)IR1
      (Jones and Gelbart, 1990)
      Name Synonyms
      Secondary FlyBase IDs
        References (4)